| Region | Level | Instrument | Region Chair | Name | School |
| 4 | SR | Flute | 01 | Martina Salinas | Charleston School of the Arts High School |
| 4 | SR | Flute | 02 | Clara Stein | Ashley Ridge High School |
| 4 | SR | Flute | 03 | Emily Folk | Summerville High School |
| 4 | SR | Flute | 04 | Noah Maier | James Island Charter High School |
| 4 | SR | Flute | 05 | Savannah Osborn | May River High School |
| 4 | SR | Flute | 06 | Isabel Favre | Wando High School |
| 4 | SR | Flute | 07 | Reagan Guy | Wando High School |
| 4 | SR | Flute | 08 | Katherine Paiz | Summerville High School |
| 4 | SR | Flute | 09 | Valerie Kempton | Ashley Ridge High School |
| 4 | SR | Flute | 10 | Ellie Garner | Charleston School of the Arts High School |
| 4 | SR | Flute | 11 | Victoria Grace Jenkins | Battery Creek High School |
| 4 | SR | Flute | 12 | Margaret Armes | Battery Creek High School |
| 4 | SR | Flute | A01 | Cecelia Favero | Summerville High School |
| 4 | SR | Flute | A02 | Makayla Stewart | West Ashley High School |
| 4 | SR | Flute | A03 | Jenna Bovell | Ashley Ridge High School |
| 4 | SR | Flute | A04 | Ella Grace Sines-Thomasson | Charleston School of the Arts High School |
| 4 | SR | Flute | A05 | Erin McHayle | Ridgeland Hardeeville High School |
| 4 | SR | Flute | A06 | Randi Hanney | Ridgeland Hardeeville High School |
| 4 | SR | Oboe | 01 | Marcus Lewis | Lucy Beckham High School |
| 4 | SR | Oboe | 02 | Kennedi Rivers | Wando High School |
| 4 | SR | Oboe | 03 | Eleanor Yarbrough | Wando High School |
| 4 | SR | Oboe | 04 | Alexander Palmer | James Island Charter High School |
| 4 | SR | Oboe | A01 | Carolyn Macklin | Charleston School of the Arts High School |
| 4 | SR | Bassoon | 01 | Eric Mays | Summerville High School |
| 4 | SR | Bassoon | 02 | Nick Gergits | Wando High School |
| 4 | SR | Bassoon | 03 | Joshua Nisoff | James Island Charter High School |
| 4 | SR | Bassoon | 04 | Ethan Huff | Wando High School |
| 4 | SR | Bassoon | A01 | Cathryn Sober | Ashley Ridge High School |
| 4 | SR | Bassoon | A02 | Evy Massey | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 01 | Carson Kenner | Wando High School |
| 4 | SR | Clarinet | 02 | Mackenzie Ring | Wando High School |
| 4 | SR | Clarinet | 03 | Ryleigh Starrett | Summerville High School |
| 4 | SR | Clarinet | 04 | Matthew Dang | Wando High School |
| 4 | SR | Clarinet | 05 | Nash Baldwin | Wando High School |
| 4 | SR | Clarinet | 06 | Everett Busch | Wando High School |
| 4 | SR | Clarinet | 07 | Alex Hearn | Summerville High School |
| 4 | SR | Clarinet | 08 | Riley Bumgardner | Wando High School |
| 4 | SR | Clarinet | 09 | Addison Wood | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 10 | Samantha Spruill | Wando High School |
| 4 | SR | Clarinet | 11 | Reilly Wellington | Summerville High School |
| 4 | SR | Clarinet | 12 | Alexander Norwood | Summerville High School |
| 4 | SR | Clarinet | 13 | Maddie Chanthabane | James Island Charter High School |
| 4 | SR | Clarinet | 14 | Abby Wimer | Wando High School |
| 4 | SR | Clarinet | 15 | Anna Terry | Wando High School |
| 4 | SR | Clarinet | 16 | Nicholson Taylor Ann | Summerville High School |
| 4 | SR | Clarinet | 17 | Sydney Kahler | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 18 | Sophia Champ | Wando High School |
| 4 | SR | Clarinet | 19 | Benjamin Nodine | Wando High School |
| 4 | SR | Clarinet | 20 | Abigail Godwin | Fort Dorchester High School |
| 4 | SR | Clarinet | 21 | Sam Henshaw | Wando High School |
| 4 | SR | Clarinet | 22 | Gabriella Hylton | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 23 | CJ Robinson | Wando High School |
| 4 | SR | Clarinet | 24 | Brooke Smith | Wando High School |
| 4 | SR | Bass Clarinet | 01 | Andrew Pitsis | Wando High School |
| 4 | SR | Bass Clarinet | 02 | Marcos Cruz | Summerville High School |
| 4 | SR | Bass Clarinet | 03 | Seth Duren | Summerville High School |
| 4 | SR | Bass Clarinet | 04 | Devin Fauver | May River High School |
| 4 | SR | Bass Clarinet | A01 | Joshua Feaster | Charleston School of the Arts High School |
| 4 | SR | Alto Sax | 01 | Jordan Brown | Summerville High School |
| 4 | SR | Alto Sax | 02 | Colin Battle | Summerville High School |
| 4 | SR | Alto Sax | 03 | Jeniya Brown | Summerville High School |
| 4 | SR | Alto Sax | 04 | Sidonie Mahon | Wando High School |
| 4 | SR | Alto Sax | 05 | Ryland Watson | Wando High School |
| 4 | SR | Alto Sax | 06 | Sean Cronin | Ashley Ridge High School |
| 4 | SR | Alto Sax | A01 | Avery Verzaal | Wando High School |
| 4 | SR | Alto Sax | A02 | Jack Matz | May River High School |
| 4 | SR | Alto Sax | A03 | Austin Walton | Charleston School of the Arts High School |
| 4 | SR | Tenor Sax | 01 | Richard Stewart | Wando High School |
| 4 | SR | Tenor Sax | 02 | Austin Hooker | First Baptist School |
| 4 | SR | Tenor Sax | A01 | Devin Dietrich | Wando High School |
| 4 | SR | Bari Sax | 01 | Kiersten Miller | Wando High School |
| 4 | SR | Trumpet | 01 | Clifton Olivia | Summerville High School |
| 4 | SR | Trumpet | 02 | Blayne Burklow | Wando High School |
| 4 | SR | Trumpet | 03 | Walker Cashon | Wando High School |
| 4 | SR | Trumpet | 04 | Flora Majkrzak | Charleston School of the Arts High School |
| 4 | SR | Trumpet | 05 | Alex Park | Charleston School of the Arts High School |
| 4 | SR | Trumpet | 06 | Shane Zbyrowski | James Island Charter High School |
| 4 | SR | Trumpet | 07 | Carter Brandt | Wando High School |
| 4 | SR | Trumpet | 08 | Jorge Martinez | Fort Dorchester High School |
| 4 | SR | Trumpet | 09 | Chaz Mulligan | Wando High School |
| 4 | SR | Trumpet | 10 | Pierson Kelley | Wando High School |
| 4 | SR | Trumpet | 11 | Patrick Higgins | Summerville High School |
| 4 | SR | Trumpet | 12 | Brooke Carlton | Wando High School |
| 4 | SR | Trumpet | 13 | Jude Martin | Summerville High School |
| 4 | SR | Trumpet | 14 | Gregory Moore | Summerville High School |
| 4 | SR | Trumpet | 15 | Gabriel Wohlfarth | James Island Charter High School |
| 4 | SR | Trumpet | 16 | Andrew Carreira | James Island Charter High School |
| 4 | SR | Trumpet | A01 | Caleb Murphy | Summerville High School |
| 4 | SR | Trumpet | A02 | Max Gair | Charleston School of the Arts High School |
| 4 | SR | Trumpet | A03 | Cole Woodard | Ashley Ridge High School |
| 4 | SR | Trumpet | A04 | Noah Zapkowski | Fort Dorchester High School |
| 4 | SR | Trumpet | A05 | Emma Wyatt | Ashley Ridge High School |
| 4 | SR | Trumpet | A06 | Emma Lanzone | May River High School |
| 4 | SR | Trumpet | A07 | Elijah Harris | Summerville High School |
| 4 | SR | Trumpet | A08 | Dooley Hiott | Colleton County High School |
| 4 | SR | Horn | 01 | Devon Nadelstumph | Wando High School |
| 4 | SR | Horn | 02 | Thomas Rush | Summerville High School |
| 4 | SR | Horn | 03 | Clifton Madelyn | Summerville High School |
| 4 | SR | Horn | 04 | Emma Bassett | Ashley Ridge High School |
| 4 | SR | Horn | 05 | Carleigh Torykian | Wando High School |
| 4 | SR | Horn | 06 | Elise Lo | Wando High School |
| 4 | SR | Horn | 07 | Cheyenne Lambton-Carr | Wando High School |
| 4 | SR | Horn | 08 | Genevieve Sjolander | Wando High School |
| 4 | SR | Horn | A01 | Brady Setser | Wando High School |
| 4 | SR | Horn | A02 | Kathleen Kidd | Wando High School |
| 4 | SR | Horn | A03 | Claire Andersen | Wando High School |
| 4 | SR | Horn | A04 | Hannah Daly | Fort Dorchester High School |
| 4 | SR | Trombone | 01 | Soren Jones | Charleston School of the Arts High School |
| 4 | SR | Trombone | 02 | Gabriel Goldman | Charleston School of the Arts High School |
| 4 | SR | Trombone | 03 | Noah Song | Wando High School |
| 4 | SR | Trombone | 04 | Leila Hollinshead | Wando High School |
| 4 | SR | Trombone | 05 | Ryan Evans | Fort Dorchester High School |
| 4 | SR | Trombone | 06 | Mallory Osborn | May River High School |
| 4 | SR | Trombone | 07 | Sam Alvey | May River High School |
| 4 | SR | Trombone | 08 | Aiden Rix | Charleston School of the Arts High School |
| 4 | SR | Trombone | 09 | Tristan Donaldson | James Island Charter High School |
| 4 | SR | Trombone | A01 | Olivia David-McNeal | Fort Dorchester High School |
| 4 | SR | Trombone | A02 | Marshall Godwin | Fort Dorchester High School |
| 4 | SR | Trombone | A03 | Miquel Johnson | Orangeburg Wilkinson Senior High School |
| 4 | SR | Trombone | A04 | Keith Jefferson | Fort Dorchester High School |
| 4 | SR | Trombone | A05 | Michael Fairey | Beaufort High School |
| 4 | SR | Euphonium | 01 | Jacob Cox | Wando High School |
| 4 | SR | Euphonium | 02 | Demahri Jackson | Ashley Ridge High School |
| 4 | SR | Euphonium | 03 | William Lamar | Charleston School of the Arts High School |
| 4 | SR | Euphonium | 04 | Jabori Carter | Burke High School |
| 4 | SR | Euphonium | A01 | Abigail Thornley | Charleston School of the Arts High School |
| 4 | SR | Euphonium | A02 | Marco Casco | Fort Dorchester High School |
| 4 | SR | Tuba | 01 | Annabelle Boozer | Wando High School |
| 4 | SR | Tuba | 02 | Alexander Wiley | Wando High School |
| 4 | SR | Tuba | 03 | Jeremiah Collins | Charleston School of the Arts High School |
| 4 | SR | Tuba | 04 | Kasyiah Dunham | Charleston School of the Arts High School |
| 4 | SR | Tuba | 05 | William Ray | Wando High School |
| 4 | SR | Tuba | 06 | Nick Cook | Charleston School of the Arts High School |
| 4 | SR | Tuba | 07 | Ryan Rodriguez | Wando High School |
| 4 | SR | Tuba | 08 | Jacob Tierney | Ashley Ridge High School |
| 4 | SR | Tuba | A01 | Roddey Sims | May River High School |
| 4 | SR | Tuba | A02 | Bashwyn Fitch | James Island Charter High School |
| 4 | SR | Bass Trombone | 01 | Eric Maciejewski | Wando High School |
| 4 | SR | Bass Trombone | A01 | Cooper Snowdon | Lucy Beckham High School |
| 4 | SR | Percussion | 01 | Dominick Hernandez | Wando High School |
| 4 | SR | Percussion | 02 | Charlie Dentzman | Wando High School |
| 4 | SR | Percussion | 03 | Kevin Maxted | Wando High School |
| 4 | SR | Percussion | 04 | Elijah Butler | Wando High School |
| 4 | SR | Percussion | 05 | Cameron Truluck | Ashley Ridge High School |
| 4 | SR | Percussion | 06 | Patrick Bailey | Summerville High School |
| 4 | SR | Percussion | 07 | Andy Hattabaugh | Ashley Ridge High School |
| 4 | SR | Percussion | A01 | Graydon Cornette | Summerville High School |
| 4 | SR | Percussion | A02 | Cole Amick | Summerville High School |
| 4 | SR | Percussion | A03 | Tanner Lawson | Summerville High School |
| 4 | SR | Percussion | A04 | Wilson Collins | Lucy Beckham High School |
| 4 | SR | Timpani | 01 | Cecilia Ollis | Wando High School |
| 4 | SR | Timpani | A01 | Zachary Lloyd | Ashley Ridge High School |