| Region | Level | Instrument | Region Chair | Name | School |
| 4 | CL | Flute | 01 | Luke Phillips | Wando High School |
| 4 | CL | Flute | 02 | Mia Liebenow | Lucy Beckham High School |
| 4 | CL | Flute | 03 | Nora Dukes | Lucy Beckham High School |
| 4 | CL | Flute | 04 | Addy Rose Knotts | Wando High School |
| 4 | CL | Flute | 05 | Sarah Hudspeth | Wando High School |
| 4 | CL | Flute | 06 | Grace Bower | Summerville High School |
| 4 | CL | Flute | 07 | Mary Alice Fairey | James Island Charter High School |
| 4 | CL | Flute | 08 | Trinity Maldonado | Summerville High School |
| 4 | CL | Flute | 09 | Brianna Tsang | Fort Dorchester High School |
| 4 | CL | Flute | 10 | Leilana Kahalehoe | Wando High School |
| 4 | CL | Flute | 11 | Annie Seabrook | Summerville High School |
| 4 | CL | Flute | 12 | Sela Guy | Wando High School |
| 4 | CL | Flute | A01 | Elsie Seay | Lucy Beckham High School |
| 4 | CL | Flute | A02 | Sara Embrey | Wando High School |
| 4 | CL | Flute | A03 | Alana Stroman | North High School |
| 4 | CL | Flute | A04 | Nikki Agina | Colleton County High School |
| 4 | CL | Flute | A05 | Kevin Sanchez | Fort Dorchester High School |
| 4 | CL | Flute | A06 | Peighton Runkel | North High School |
| 4 | CL | Oboe | 01 | Ava Terzulli | Summerville High School |
| 4 | CL | Oboe | 02 | Kylie Kothera | Charleston School of the Arts High School |
| 4 | CL | Oboe | 03 | Meghan Zimmerman | Wando High School |
| 4 | CL | Oboe | 04 | Wyatt Savage | Summerville High School |
| 4 | CL | Bassoon | 01 | Beckham Schou | Wando High School |
| 4 | CL | Bassoon | 02 | McKayla Sturgill | Summerville High School |
| 4 | CL | Clarinet | 01 | Kamrin Mungin | Charleston School of the Arts High School |
| 4 | CL | Clarinet | 02 | Michael Ferrara | Wando High School |
| 4 | CL | Clarinet | 03 | Breeden Hall | Wando High School |
| 4 | CL | Clarinet | 04 | Stephean Judy | Ashley Ridge High School |
| 4 | CL | Clarinet | 05 | Rylee Boosinger | Ashley Ridge High School |
| 4 | CL | Clarinet | 06 | Avarie Lyon | Wando High School |
| 4 | CL | Clarinet | 07 | Demetre Ray | Fort Dorchester High School |
| 4 | CL | Clarinet | 08 | Emma Brubaker | Charleston School of the Arts High School |
| 4 | CL | Clarinet | 09 | Rocio Arroyo | Summerville High School |
| 4 | CL | Clarinet | 10 | Presley Osborne | Lucy Beckham High School |
| 4 | CL | Clarinet | 11 | Marco Le | Fort Dorchester High School |
| 4 | CL | Clarinet | 12 | Anthony Moore | Fort Dorchester High School |
| 4 | CL | Clarinet | 13 | Xander Beaver | Bluffton High School |
| 4 | CL | Clarinet | 14 | Ronson Parker | Fort Dorchester High School |
| 4 | CL | Clarinet | 15 | Aubrey Smith | Fort Dorchester High School |
| 4 | CL | Clarinet | 16 | Lucas Alexander | Ashley Ridge High School |
| 4 | CL | Clarinet | 17 | Mia Voelker | Charleston School of the Arts High School |
| 4 | CL | Clarinet | 18 | Juliana Tinoco | James Island Charter High School |
| 4 | CL | Clarinet | 19 | Nicholas Christov | Fort Dorchester High School |
| 4 | CL | Clarinet | 20 | Savannah Bowlin | Lucy Beckham High School |
| 4 | CL | Clarinet | 21 | Peyton Moody | Wando High School |
| 4 | CL | Clarinet | 22 | Alyssa Cross | Ashley Ridge High School |
| 4 | CL | Clarinet | 23 | Claire Gibson | Wando High School |
| 4 | CL | Clarinet | 24 | Ren Takemoto | Wando High School |
| 4 | CL | Bass Clarinet | 01 | Caleb Draisen | Beaufort High School |
| 4 | CL | Bass Clarinet | 02 | Solé Bennett | Ridgeland Hardeeville High School |
| 4 | CL | Bass Clarinet | 03 | Kaitlyn Barnard | Wando High School |
| 4 | CL | Bass Clarinet | 04 | Genevieve Spada | Summerville High School |
| 4 | CL | Alto Sax | 01 | So Takemoto | Wando High School |
| 4 | CL | Alto Sax | 02 | Lexie Allen | Wando High School |
| 4 | CL | Alto Sax | 03 | James Rosenthal | Lucy Beckham High School |
| 4 | CL | Alto Sax | 04 | Jason Wan | Charleston School of the Arts High School |
| 4 | CL | Alto Sax | 05 | Graham Norman | Wando High School |
| 4 | CL | Alto Sax | 06 | Jackson Hooks | Wando High School |
| 4 | CL | Alto Sax | A01 | Colby Reese | Wando High School |
| 4 | CL | Alto Sax | A02 | Mahish Lowkie | Ashley Ridge High School |
| 4 | CL | Alto Sax | A03 | Natalie Nickison | Ashley Ridge High School |
| 4 | CL | Tenor Sax | 01 | Remy Levesque | Wando High School |
| 4 | CL | Tenor Sax | 02 | Emma Ward | Fort Dorchester High School |
| 4 | CL | Tenor Sax | A01 | Kyle Angelich | Wando High School |
| 4 | CL | Bari Sax | 01 | Francesco Giuliano | Wando High School |
| 4 | CL | Bari Sax | A01 | Oliver Murrell | Lucy Beckham High School |
| 4 | CL | Trumpet | 01 | Aaron Ruopp | Charleston School of the Arts High School |
| 4 | CL | Trumpet | 02 | Ian Rutledge | Lucy Beckham High School |
| 4 | CL | Trumpet | 03 | Christina Vines | James Island Charter High School |
| 4 | CL | Trumpet | 04 | Emerson Mackes | Wando High School |
| 4 | CL | Trumpet | 05 | Adam Sokoloski | Wando High School |
| 4 | CL | Trumpet | 06 | Miles Baldwin | Wando High School |
| 4 | CL | Trumpet | 07 | Clara Danner | Wando High School |
| 4 | CL | Trumpet | 08 | Hayden Pinto | Wando High School |
| 4 | CL | Trumpet | 09 | Stewart Hayes | Ashley Ridge High School |
| 4 | CL | Trumpet | 10 | Benjamin Schell | West Ashley High School |
| 4 | CL | Trumpet | 11 | Shayna Gardner | Ashley Ridge High School |
| 4 | CL | Trumpet | 12 | Neil Durlach | Lucy Beckham High School |
| 4 | CL | Trumpet | 13 | Nicholas Severance | Charleston School of the Arts High School |
| 4 | CL | Trumpet | 14 | Christopher Kroamer | Bluffton High School |
| 4 | CL | Trumpet | 15 | Matthew deBarros | Lucy Beckham High School |
| 4 | CL | Trumpet | 16 | Avery Gordon | James Island Charter High School |
| 4 | CL | Trumpet | A01 | Elijah Green | Ashley Ridge High School |
| 4 | CL | Trumpet | A02 | Emmy McDonald | Fort Dorchester High School |
| 4 | CL | Trumpet | A03 | Cameron Thomson | Wando High School |
| 4 | CL | Trumpet | A04 | Evan Grochowsi | Ashley Ridge High School |
| 4 | CL | Trumpet | A05 | David Jonas | Ashley Ridge High School |
| 4 | CL | Trumpet | A06 | Jack Helmueller | Summerville High School |
| 4 | CL | Trumpet | A07 | Ethan Evans | Ashley Ridge High School |
| 4 | CL | Trumpet | A08 | Chris Perez | Fort Dorchester High School |
| 4 | CL | Horn | 01 | Nicole Pace | Wando High School |
| 4 | CL | Horn | 02 | Grange Simons | Lucy Beckham High School |
| 4 | CL | Horn | 03 | Erika Oltmann | Wando High School |
| 4 | CL | Horn | 04 | Caleb Bannister | Fort Dorchester High School |
| 4 | CL | Horn | 05 | Zalynn Rodwell | Charleston School of the Arts High School |
| 4 | CL | Horn | 06 | Zachary Wiley | Wando High School |
| 4 | CL | Horn | 07 | Pete Harden | Lucy Beckham High School |
| 4 | CL | Horn | 08 | Francis Waddell | Fort Dorchester High School |
| 4 | CL | Horn | A01 | Matthew Strickland | Fort Dorchester High School |
| 4 | CL | Horn | A02 | Alexandra Lettau | Ashley Ridge High School |
| 4 | CL | Horn | A03 | Ella Aikman | Charleston School of the Arts High School |
| 4 | CL | Horn | A04 | Nathan Ernst | Wando High School |
| 4 | CL | Trombone | 01 | Stephen Carlisle | Lucy Beckham High School |
| 4 | CL | Trombone | 02 | Madison Lott | Summerville High School |
| 4 | CL | Trombone | 03 | Charles Rostance | Ashley Ridge High School |
| 4 | CL | Trombone | 04 | Ethan Arthur | Wando High School |
| 4 | CL | Trombone | 05 | Zachary Winston | Wando High School |
| 4 | CL | Trombone | 06 | August Boozer | Lucy Beckham High School |
| 4 | CL | Trombone | 07 | Conor Barton | Wando High School |
| 4 | CL | Trombone | 08 | Ryan Lockett | Lucy Beckham High School |
| 4 | CL | Trombone | 09 | Clifton Mason | Summerville High School |
| 4 | CL | Trombone | A01 | Julia Cherry | Wando High School |
| 4 | CL | Trombone | A02 | Corbin Harp | Wando High School |
| 4 | CL | Trombone | A03 | Corinne Crumpton | James Island Charter High School |
| 4 | CL | Trombone | A04 | Noah Counts | James Island Charter High School |
| 4 | CL | Trombone | A05 | Nalani White | Fort Dorchester High School |
| 4 | CL | Euphonium | 01 | Fritz Kuester | Wando High School |
| 4 | CL | Euphonium | 02 | Adam Chavez | Wando High School |
| 4 | CL | Euphonium | 03 | Isabella Nichols | Lucy Beckham High School |
| 4 | CL | Euphonium | 04 | Jackson Fox | Charleston School of the Arts High School |
| 4 | CL | Euphonium | A01 | Hope Young | Ashley Ridge High School |
| 4 | CL | Euphonium | A02 | BRAXTYN NETTLES | Edisto High School |
| 4 | CL | Tuba | 01 | Aidan Pollitt | Ashley Ridge High School |
| 4 | CL | Tuba | 02 | Charlie Pratt | Wando High School |
| 4 | CL | Tuba | 03 | Eddie Evan Perry | North High School |
| 4 | CL | Tuba | 04 | Aiden Harvey | Bluffton High School |
| 4 | CL | Tuba | 05 | Max Thomas Trett | Lucy Beckham High School |
| 4 | CL | Tuba | 06 | Caleb Young | Wando High School |
| 4 | CL | Tuba | 07 | Seth Harper | Ashley Ridge High School |
| 4 | CL | Tuba | 08 | GABRIEL BROWN | Edisto High School |
| 4 | CL | Percussion | 01 | Kyle Knapek | Fort Dorchester High School |
| 4 | CL | Percussion | 02 | Javien Benefield | Fort Dorchester High School |
| 4 | CL | Percussion | 03 | Braeden Hursey | Summerville High School |
| 4 | CL | Percussion | 04 | Adam Hattabaugh | Ashley Ridge High School |
| 4 | CL | Percussion | 05 | Jeremy Zetrouer | Wando High School |
| 4 | CL | Percussion | 06 | Logan Ryle | Wando High School |
| 4 | CL | Percussion | 07 | Donovan McClain | Lucy Beckham High School |
| 4 | CL | Percussion | A01 | Levi Bloxom | Wando High School |
| 4 | CL | Percussion | A02 | Nicholas Robinson | Fort Dorchester High School |
| 4 | CL | Percussion | A03 | Lukas Garvin | James Island Charter High School |
| 4 | CL | Percussion | A04 | Skyler Waddell | Charleston School of the Arts High School |
| 4 | CL | Timpani | 01 | Remington Joy | Wando High School |
| 4 | CL | Timpani | A01 | Colsen Guy | Wando High School |