| Reg | Level | Instrument | Chair | Name | School |
| 5 | SR | Flute | 01 | Taylor Pittman | Stratford High School |
| 5 | SR | Flute | 02 | Ronreguss Grant | Goose Creek High School |
| 5 | SR | Flute | 03 | Jennifer Polfleit | Stratford High School |
| 5 | SR | Flute | 04 | Madison Liles | Cane Bay High School |
| 5 | SR | Flute | 05 | Jemiah Williams | Stratford High School |
| 5 | SR | Flute | 06 | Grace Wallace | Cane Bay High School |
| 5 | SR | Flute | 07 | Jaela Simms | Sumter High School |
| 5 | SR | Flute | 08 | Madison Davis | Aynor High School |
| 5 | SR | Flute | 09 | Miranda Byork | North Myrtle Beach High School |
| 5 | SR | Flute | 10 | Rachel Wyatt | Stratford High School |
| 5 | SR | Flute | 11 | Angel Hunt | Dillon High School |
| 5 | SR | Flute | 12 | Cassidy Bean | Carolina Forest High School |
| 5 | SR | Flute | A01 | Jenny Le | Hanahan High School |
| 5 | SR | Flute | A02 | YaNeisha Tedder | Darlington High School |
| 5 | SR | Flute | A03 | Sydney Ballard | Hanahan High School |
| 5 | SR | Flute | A04 | Landry Foye | Philip Simmons High School |
| 5 | SR | Flute | A05 | Lilly Ellis | Goose Creek High School |
| 5 | SR | Flute | A06 | Elizabeth Rice | Myrtle Beach High School |
| 5 | SR | Oboe | 01 | Ashlynn Andrews | Hanahan High School |
| 5 | SR | Oboe | 02 | Michela Urso | Carolina Forest High School |
| 5 | SR | Oboe | 03 | Gretchen Burgess | Stratford High School |
| 5 | SR | Oboe | 04 | Robert Burleson | Goose Creek High School |
| 5 | SR | Bassoon | 01 | Preston Lee | Stratford High School |
| 5 | SR | Bassoon | 02 | Aaron Nealy | Carolina Forest High School |
| 5 | SR | Clarinet | 01 | Teague McCracken | Stratford High School |
| 5 | SR | Clarinet | 02 | Ansley Moore | West Florence High School |
| 5 | SR | Clarinet | 03 | Logan Szyjkowski | Stratford High School |
| 5 | SR | Clarinet | 04 | Hanah Kerrigan | Cane Bay High School |
| 5 | SR | Clarinet | 05 | Nia Misuraca | Hanahan High School |
| 5 | SR | Clarinet | 06 | Jerkaiya Carter | Goose Creek High School |
| 5 | SR | Clarinet | 07 | Savannah Holley | Goose Creek High School |
| 5 | SR | Clarinet | 08 | Victor Sanchez | Conway High School |
| 5 | SR | Clarinet | 09 | Dana Joe | Darlington High School |
| 5 | SR | Clarinet | 10 | Isabelle Cabales | Goose Creek High School |
| 5 | SR | Clarinet | 11 | Donovan Massey | Saint James High School |
| 5 | SR | Clarinet | 12 | Emma Grimes | Carolina Forest High School |
| 5 | SR | Clarinet | 13 | Shaniya McInnis | Dillon High School |
| 5 | SR | Clarinet | 14 | Maya Youssef | Hanahan High School |
| 5 | SR | Clarinet | 15 | Emma Butch | Stratford High School |
| 5 | SR | Clarinet | 16 | Antania McCollum | Dillon High School |
| 5 | SR | Clarinet | 17 | Kierra Robertson | Sumter High School |
| 5 | SR | Clarinet | 18 | Shalynn Hayes | Sumter High School |
| 5 | SR | Clarinet | 19 | Nastajia Hamilton | Manning High School |
| 5 | SR | Clarinet | 20 | Briana Scott | Darlington High School |
| 5 | SR | Clarinet | 21 | Brianna Johnson | Georgetown High School |
| 5 | SR | Clarinet | 22 | Shymia Scipio | Mayo High School |
| 5 | SR | Clarinet | 23 | Ryan Bishop | Philip Simmons High School |
| 5 | SR | Clarinet | 24 | Emily Lamere | Central High School |
| 5 | SR | Clarinet | A01 | Kayla Morrin | Carolina Forest High School |
| 5 | SR | Clarinet | A02 | Sidney Clark | Hanahan High School |
| 5 | SR | Clarinet | A03 | Savannah Pender | S.C. Governor’s School for Science & Mathematics |
| 5 | SR | Clarinet | A04 | Yesenia Martinez | North Myrtle Beach High School |
| 5 | SR | Clarinet | A05 | Haley Polson | Carolina Forest High School |
| 5 | SR | Clarinet | A06 | Arlionna Jenkins | Timberland High School |
| 5 | SR | Clarinet | A07 | Dasia Council | Carolina Forest High School |
| 5 | SR | Clarinet | A08 | Alex Santos | Stratford High School |
| 5 | SR | Bass Clarinet | 01 | Allyssa Weir | Stratford High School |
| 5 | SR | Bass Clarinet | 02 | Keevon Fullard | Sumter High School |
| 5 | SR | Bass Clarinet | 03 | Maria Munoz | Darlington High School |
| 5 | SR | Bass Clarinet | 04 | Angel Peterson | Stratford High School |
| 5 | SR | Contra Clarinet | 01 | Esteban Mattei | Stratford High School |
| 5 | SR | Contra Clarinet | 02 | Jada Davis | Dillon High School |
| 5 | SR | Contra Clarinet | A01 | Ashley Hamilton | Goose Creek High School |
| 5 | SR | Alto Sax | 01 | Carlton Williams | Cane Bay High School |
| 5 | SR | Alto Sax | 02 | Sarah Dumont | Stratford High School |
| 5 | SR | Alto Sax | 03 | McKinley Mingacci | Stratford High School |
| 5 | SR | Alto Sax | 04 | Justin Gilkerson | Stratford High School |
| 5 | SR | Alto Sax | 05 | Jackson Peavy | Hanahan High School |
| 5 | SR | Alto Sax | 06 | Leslie Orellana | Sumter High School |
| 5 | SR | Alto Sax | A01 | Kevin Spivey | Stratford High School |
| 5 | SR | Alto Sax | A02 | La’India Chapman | Darlington High School |
| 5 | SR | Alto Sax | A03 | Jamont McRae | Dillon High School |
| 5 | SR | Tenor Sax | 01 | Gabriel Joda | Hanahan High School |
| 5 | SR | Tenor Sax | 02 | Landon Bailey | Sumter High School |
| 5 | SR | Tenor Sax | A01 | Chase Sawyer | Latta High School |
| 5 | SR | Bari Sax | 01 | Christopher Melendez | Socastee High School |
| 5 | SR | Bari Sax | A01 | Christopher Hancock | Darlington High School |
| 5 | SR | Trumpet | 01 | Jacob Spell | S.C. Governor’s School for the Arts and Humanities – Region 5 |
| 5 | SR | Trumpet | 02 | Logan Carpenter | Stratford High School |
| 5 | SR | Trumpet | 03 | Greg Belisle | Cane Bay High School |
| 5 | SR | Trumpet | 04 | Hannah Martin | Philip Simmons High School |
| 5 | SR | Trumpet | 05 | Storm Milan | Socastee High School |
| 5 | SR | Trumpet | 06 | Michael Walton | Carolina Forest High School |
| 5 | SR | Trumpet | 07 | Alex Vlandis | Myrtle Beach High School |
| 5 | SR | Trumpet | 08 | Ben Battelini | Stratford High School |
| 5 | SR | Trumpet | 09 | Jack DeRiso | Saint James High School |
| 5 | SR | Trumpet | 10 | Thomas Hirak | Sumter High School |
| 5 | SR | Trumpet | 11 | Jacob Zenner | Goose Creek High School |
| 5 | SR | Trumpet | 12 | Aniyah Williams | Timberland High School |
| 5 | SR | Trumpet | 13 | Allison Brown | Cheraw High School |
| 5 | SR | Trumpet | 14 | Terry Boyd | Cross High School |
| 5 | SR | Trumpet | 15 | Ashanti Milling | Darlington High School |
| 5 | SR | Trumpet | 16 | Olivia Wooten | Carolina Forest High School |
| 5 | SR | Trumpet | A01 | Kenneth Wingate Jr. | Hartsville High School |
| 5 | SR | Trumpet | A02 | Mallory Blanding | Manning High School |
| 5 | SR | Trumpet | A03 | Austin Quiaem | Goose Creek High School |
| 5 | SR | Trumpet | A04 | Christian Wineglass | Conway High School |
| 5 | SR | Trumpet | A05 | Evan Ewing | Saint James High School |
| 5 | SR | Trumpet | A06 | Jose Jimenez-Rodriguez | Hartsville High School |
| 5 | SR | Trumpet | A07 | Glenn Braden | Sumter High School |
| 5 | SR | Trumpet | A08 | Cody Hodges | Sumter High School |
| 5 | SR | Horn | 01 | Abigail Stewart | S.C. Governor’s School for the Arts and Humanities – Region 5 |
| 5 | SR | Horn | 02 | Isabella Hirsch | Carolina Forest High School |
| 5 | SR | Horn | 03 | Mia Honeyman | Stratford High School |
| 5 | SR | Horn | 04 | Jada Goff | Socastee High School |
| 5 | SR | Horn | 05 | Colby Gerald | Loris High School |
| 5 | SR | Horn | 06 | Evie O’Saben | Stratford High School |
| 5 | SR | Horn | 07 | DeAndre Lloyd | Goose Creek High School |
| 5 | SR | Horn | 08 | Tucker Richardson | Carolina Forest High School |
| 5 | SR | Horn | A01 | Ashton Turner | Dillon High School |
| 5 | SR | Horn | A02 | Laney Midgley | Cheraw High School |
| 5 | SR | Horn | A03 | Fiona Rodriguez | Conway High School |
| 5 | SR | Horn | A04 | Carson Mack | Central High School |
| 5 | SR | Trombone | 01 | T.J. Pitchford | Stratford High School |
| 5 | SR | Trombone | 02 | Olivia Walker | Stratford High School |
| 5 | SR | Trombone | 03 | Preston Bishop-Burns | North Myrtle Beach High School |
| 5 | SR | Trombone | 04 | Amir Mclellan | Dillon High School |
| 5 | SR | Trombone | 05 | James Suggs | South Florence High School |
| 5 | SR | Trombone | 06 | Elsie Brumett | Chesterfield High School |
| 5 | SR | Trombone | 07 | Ethan Strickland | Wilson High School |
| 5 | SR | Trombone | 08 | Ev Seay | Latta High School |
| 5 | SR | Trombone | 09 | Amelia Palmer | Stratford High School |
| 5 | SR | Trombone | A01 | Mary McBane | Hanahan High School |
| 5 | SR | Trombone | A02 | Daniel Sturgill | Hartsville High School |
| 5 | SR | Trombone | A03 | Matthew Villanueva | Goose Creek High School |
| 5 | SR | Trombone | A04 | Colby Davenport | Cane Bay High School |
| 5 | SR | Trombone | A05 | Miriam Jackson | Cross High School |
| 5 | SR | Euphonium | 01 | Jones Brown | Carolina Forest High School |
| 5 | SR | Euphonium | 02 | Ben Asulin | Saint James High School |
| 5 | SR | Euphonium | 03 | Brock Mack | Dillon High School |
| 5 | SR | Euphonium | 04 | Mai Floyd | Conway High School |
| 5 | SR | Euphonium | A01 | David Felix | Wilson High School |
| 5 | SR | Euphonium | A02 | Elizabeth Watts | Sumter High School |
| 5 | SR | Tuba | 01 | Jackson Bryanna | Timberland High School |
| 5 | SR | Tuba | 02 | Quandarius Kelly | Chesterfield High School |
| 5 | SR | Tuba | 03 | Carson Woodham | Cheraw High School |
| 5 | SR | Tuba | 04 | Nicholas Joyner | Darlington High School |
| 5 | SR | Tuba | 05 | Derek Taylor | Goose Creek High School |
| 5 | SR | Tuba | 06 | Anthony Degrazio | Lakewood High School |
| 5 | SR | Tuba | 07 | Jayvon Simmons | Goose Creek High School |
| 5 | SR | Tuba | 08 | Jackson Sfreddo | Stratford High School |
| 5 | SR | Tuba | A01 | Jordan Felix | Carolina Forest High School |
| 5 | SR | Tuba | A02 | Jack Kibler | Waccamaw High School |
| 5 | SR | Tuba | A03 | Noah Petty | Stratford High School |
| 5 | SR | Tuba | A04 | Symeon Kennedy | Goose Creek High School |
| 5 | SR | Bass Trombone | 01 | Te’Ondrus Billie | Sumter High School |
| 5 | SR | Bass Trombone | A01 | Reggie Graves | Dillon High School |
| 5 | SR | Percussion | 01 | Hannah Sturdivant | Cane Bay High School |
| 5 | SR | Percussion | 02 | Wyatt Carhart | Hanahan High School |
| 5 | SR | Percussion | 03 | Calece Kornahrens | Hanahan High School |
| 5 | SR | Percussion | 04 | Robert Bush | Hanahan High School |
| 5 | SR | Percussion | 05 | Edwin Tyson | Hanahan High School |
| 5 | SR | Percussion | 06 | Jessica Rock | Cane Bay High School |
| 5 | SR | Percussion | 07 | Chase Mathews | Cane Bay High School |
| 5 | SR | Percussion | A01 | Connor Brunson | Hartsville High School |
| 5 | SR | Percussion | A02 | Wesley Bower | West Florence High School |
| 5 | SR | Percussion | A03 | Thomas Bazzle | Hanahan High School |
| 5 | SR | Percussion | A04 | Harold Chandler | Goose Creek High School |
| 5 | SR | Timpani | 01 | Covington Loftus | Waccamaw High School |
| 5 | SR | Timpani | A01 | Betty Rugema | Goose Creek High School |