| Region | Level | Instrument | Chair | Name | School |
| 1 | SR | Flute | 01 | Grace Burd | Easley High School |
| 1 | SR | Flute | 02 | Emiliy Pliauplis | Easley High School |
| 1 | SR | Flute | 03 | Emma Swire-Clark | Wren High School |
| 1 | SR | Flute | 04 | Tonia Ford | Pickens High School |
| 1 | SR | Flute | 05 | Megan Eubanks | Mauldin High School |
| 1 | SR | Flute | 06 | Isabella Mahaffey | Easley High School |
| 1 | SR | Flute | 07 | Lindsey Fromknecht | Southside High School |
| 1 | SR | Flute | 08 | Emma Mecklenburg | Christ Church Episcopal School |
| 1 | SR | Flute | 09 | Megan Flower | Bob Jones Academy |
| 1 | SR | Flute | 10 | Meredith Clem | Liberty High School |
| 1 | SR | Flute | 11 | Keely McCabe | West-Oak Senior High School |
| 1 | SR | Flute | 12 | Abby McAninch | Blue Ridge High School |
| 1 | SR | Oboe | 01 | Maxwell Canipe | Greer High School |
| 1 | SR | Oboe | 02 | Daniel Gardner | Greenville High School |
| 1 | SR | Oboe | 03 | Ashlin Deatherage | West-Oak Senior High School |
| 1 | SR | Oboe | 04 | Addie Townsend | Travelers Rest High School |
| 1 | SR | Bassoon | 01 | Claudia Sanders | West-Oak Senior High School |
| 1 | SR | Bassoon | 02 | Isabella Young | Easley High School |
| 1 | SR | Bassoon | 03 | Olivia Ladines | Pendleton High School |
| 1 | SR | Clarinet | 01 | Jaime Ruiz | Easley High School |
| 1 | SR | Clarinet | 02 | Micah Trotter | Powdersville High School |
| 1 | SR | Clarinet | 03 | Rylee Jackson | Easley High School |
| 1 | SR | Clarinet | 04 | Heinrich Gottberg | Hillcrest High School (Greenville) |
| 1 | SR | Clarinet | 05 | Colin Stephens | Wade Hampton High School (Greenville) |
| 1 | SR | Clarinet | 06 | Dean Centa | Mauldin High School |
| 1 | SR | Clarinet | 07 | Riley Callahan | Walhalla Senior High School |
| 1 | SR | Clarinet | 08 | Ali Johnson | Pendleton High School |
| 1 | SR | Clarinet | 09 | Jesse Vite | Powdersville High School |
| 1 | SR | Clarinet | 10 | Lauren Suddeth | Daniel High School |
| 1 | SR | Clarinet | 11 | Joshua Drake | Daniel High School |
| 1 | SR | Clarinet | 12 | Courtney Fuller | J.L. Mann High School |
| 1 | SR | Clarinet | 13 | Jocelyn Provonost | Seneca Senior High School |
| 1 | SR | Clarinet | 14 | Marlee Smith | Greer High School |
| 1 | SR | Clarinet | 15 | Kaitlyn Hall | Riverside High School |
| 1 | SR | Clarinet | 16 | Jordan Cummings | Easley High School |
| 1 | SR | Clarinet | 17 | Mary Evelyn Stansell | Westside High School |
| 1 | SR | Clarinet | 18 | Alexis Burson | Seneca Senior High School |
| 1 | SR | Clarinet | 19 | Maria Micozzi | Mauldin High School |
| 1 | SR | Clarinet | 20 | Deanna Fulton | Greenville Tech Charter High School |
| 1 | SR | Clarinet | 21 | Summer Thompson | Blue Ridge High School |
| 1 | SR | Clarinet | 22 | Melina Lettieri | Woodmont High School |
| 1 | SR | Clarinet | 23 | Emillio Bacerra | T.L. Hanna High School |
| 1 | SR | Clarinet | 24 | Ethan Calderon | Riverside High School |
| 1 | SR | Bass Clarinet | 01 | Gwendolyn Krieger | Daniel High School |
| 1 | SR | Bass Clarinet | 02 | Mary Corley | Pendleton High School |
| 1 | SR | Bass Clarinet | 03 | Samantha Ryan | The Fine Arts Center |
| 1 | SR | Bass Clarinet | 04 | Kimberly Garcia | Walhalla Senior High School |
| 1 | SR | Contra Clarinet | 01 | Luke Smith | West-Oak Senior High School |
| 1 | SR | Contra Clarinet | 02 | Emily Peterson | Mauldin High School |
| 1 | SR | Alto Sax | 01 | Jieying Tong | Riverside High School |
| 1 | SR | Alto Sax | 02 | Aaron Schickler | Woodmont High School |
| 1 | SR | Alto Sax | 03 | Tristan Bolding | Pickens High School |
| 1 | SR | Alto Sax | 04 | Matthew Park | Daniel High School |
| 1 | SR | Alto Sax | 05 | Andrew Wang | Daniel High School |
| 1 | SR | Alto Sax | 06 | Scott Salinas | Mauldin High School |
| 1 | SR | Tenor Sax | 01 | Max Heckman | Greer High School |
| 1 | SR | Tenor Sax | 02 | Deven Smith | Easley High School |
| 1 | SR | Bari Sax | 01 | Domynic Reed | West-Oak Senior High School |
| 1 | SR | Trumpet | 01 | Anna Townsend | Bob Jones Academy |
| 1 | SR | Trumpet | 02 | Kaylyn Good | Blue Ridge High School |
| 1 | SR | Trumpet | 03 | Connor Nelson | Mauldin High School |
| 1 | SR | Trumpet | 04 | Nina Freytag | Hillcrest High School (Greenville) |
| 1 | SR | Trumpet | 05 | Noah Factor | Daniel High School |
| 1 | SR | Trumpet | 06 | Tyler Barnes | Belton Honea Path High School |
| 1 | SR | Trumpet | 07 | Savannah Colliver | Mauldin High School |
| 1 | SR | Trumpet | 08 | Leo Markowitz | Greenville Tech Charter High School |
| 1 | SR | Trumpet | 09 | Griffin Howland | Daniel High School |
| 1 | SR | Trumpet | 10 | Jake Cribley | J.L. Mann High School |
| 1 | SR | Trumpet | 11 | Christopher Blount | Mauldin High School |
| 1 | SR | Trumpet | 12 | Emily Orr | Bob Jones Academy |
| 1 | SR | Trumpet | 13 | Jacob Hayes | Pendleton High School |
| 1 | SR | Trumpet | 14 | Bryson Keefe | Blue Ridge High School |
| 1 | SR | Trumpet | 15 | Jack Disbrow | Mauldin High School |
| 1 | SR | Trumpet | 16 | Luke Robinson | West-Oak Senior High School |
| 1 | SR | Horn | 01 | Tyler Gillespie | S.C. Governor’s Humanities – REGION 1 |
| 1 | SR | Horn | 02 | Emily Holliday | Pickens High School |
| 1 | SR | Horn | 03 | Hayes Oliver | Powdersville High School |
| 1 | SR | Horn | 04 | Caitlyn Howard | Travelers Rest High School |
| 1 | SR | Horn | 05 | Christian Prins | Easley High School |
| 1 | SR | Horn | 06 | Alex Green | Greer High School |
| 1 | SR | Horn | 07 | Garrett Thrasher | Pendleton High School |
| 1 | SR | Horn | 08 | Braden Duncan | West-Oak Senior High School |
| 1 | SR | Trombone | 01 | Nicholas Rich | Travelers Rest High School |
| 1 | SR | Trombone | 02 | Nathaniel Hiott | Daniel High School |
| 1 | SR | Trombone | 03 | Brandon Beck | Mauldin High School |
| 1 | SR | Trombone | 04 | Joshua Guy | Mauldin High School |
| 1 | SR | Trombone | 05 | Keven Shumate | Easley High School |
| 1 | SR | Trombone | 06 | Michael Davis | Powdersville High School |
| 1 | SR | Trombone | 07 | Jack Cofer | Bob Jones Academy |
| 1 | SR | Trombone | 08 | Bridger Gantt | Easley High School |
| 1 | SR | Trombone | 09 | Dakota Callahan | Travelers Rest High School |
| 1 | SR | Euphonium | 01 | Richard McDonald | Daniel High School |
| 1 | SR | Euphonium | 02 | Conner Christ | Hampton Park Christian School |
| 1 | SR | Euphonium | 03 | Titus McCuthchen | Greer High School |
| 1 | SR | Euphonium | 04 | Ian Jackson | Easley High School |
| 1 | SR | Tuba | 01 | Ian Wallace | West-Oak Senior High School |
| 1 | SR | Tuba | 02 | Zach Sumney | Pendleton High School |
| 1 | SR | Tuba | 03 | Scott Buie | Mauldin High School |
| 1 | SR | Tuba | 04 | Preston Smith | Riverside High School |
| 1 | SR | Tuba | 05 | Alex Butts | Pickens High School |
| 1 | SR | Tuba | 06 | Sarah Zaw | Mauldin High School |
| 1 | SR | Tuba | 07 | Kalieb Turner | Powdersville High School |
| 1 | SR | Tuba | 08 | Tyler McAdams | Travelers Rest High School |
| 1 | SR | Percussion | 01 | Jacob Zirbel | Walhalla Senior High School |
| 1 | SR | Percussion | 02 | Benjamin McIntyre | Daniel High School |
| 1 | SR | Percussion | 03 | Sam Wyant | Daniel High School |
| 1 | SR | Percussion | 04 | Adam Finkelstein | The Fine Arts Center |
| 1 | SR | Percussion | 05 | Jacob Capps | Easley High School |
| 1 | SR | Percussion | 06 | Dalton East | Pickens High School |
| 1 | SR | Percussion | 07 | Micaiah Corbitt | The Fine Arts Center |
| 1 | SR | Timpani | 01 | Benton Halbig | Seneca Senior High School |