| Region | Level | Instrument | Chair | Name | School |
| 5 | JR | Flute | 01 | Lacey Bryant | Westview Middle School (Goose Creek) |
| 5 | JR | Flute | 02 | Wanda Hardy | Westview Middle School (Goose Creek) |
| 5 | JR | Flute | 03 | Baird Stewart | Forestbrook Middle School |
| 5 | JR | Flute | 04 | Grace Espiritu | Marrington Middle School |
| 5 | JR | Flute | 05 | Armstrong Godric | St. Anthony Catholic School |
| 5 | JR | Flute | 06 | Layna Melendez | Cane Bay Middle School |
| 5 | JR | Flute | 07 | Emma Hatfield | Westview Middle School (Goose Creek) |
| 5 | JR | Flute | 08 | Melvin Mikell | Westview Middle School (Goose Creek) |
| 5 | JR | Flute | 09 | Mohin Amin | Williams Middle School |
| 5 | JR | Flute | 10 | Breeanna Shelton | Sangaree Middle School |
| 5 | JR | Flute | 11 | Ethan Marquez | Hanahan Middle School |
| 5 | JR | Flute | 12 | Marlen Sanchez | St. James Middle School |
| 5 | JR | Flute | A01 | Josefina Gomez | New Heights Middle School |
| 5 | JR | Flute | A02 | Taryn Pitchford | Sangaree Middle School |
| 5 | JR | Flute | A03 | Connor Vongsaly | Marrington Middle School |
| 5 | JR | Flute | A04 | Rachel Byers | Ten Oaks Middle School |
| 5 | JR | Flute | A05 | Paris Nelson | Dillon Middle School |
| 5 | JR | Flute | A06 | Esmeralda Hernandez | Ten Oaks Middle School |
| 5 | JR | Flute | A07 | Hayden Rogers | Georgetown Middle School |
| 5 | JR | Flute | A08 | Avary Harrelson | Aynor Middle School |
| 5 | JR | Flute | A09 | Allison Glover | North Myrtle Beach Middle School |
| 5 | JR | Flute | A10 | Hailey Jones | Sangaree Middle School |
| 5 | JR | Oboe | 01 | Alan Bao | Ten Oaks Middle School |
| 5 | JR | Oboe | 02 | Oben Ebai | Cane Bay Middle School |
| 5 | JR | Oboe | 03 | Francesca Urso | Ten Oaks Middle School |
| 5 | JR | Oboe | 04 | Alex Hamilton | Daniel Island Middle School |
| 5 | JR | Bassoon | 01 | Ava McDonald | Daniel Island Middle School |
| 5 | JR | Bassoon | 02 | Ian Hand | Ocean Bay Middle School |
| 5 | JR | Bassoon | 03 | Micah Hutto | Dillon Middle School |
| 5 | JR | Clarinet | 01 | Scarlett Evans | Hanahan Middle School |
| 5 | JR | Clarinet | 02 | Sam Crabtree | Marrington Middle School |
| 5 | JR | Clarinet | 03 | Alayna Williams | Ten Oaks Middle School |
| 5 | JR | Clarinet | 04 | Vanessa Scotti | Ten Oaks Middle School |
| 5 | JR | Clarinet | 05 | Jose Arana | Sangaree Middle School |
| 5 | JR | Clarinet | 06 | Jordan Allen | Cane Bay Middle School |
| 5 | JR | Clarinet | 07 | Bryan Chavez | Georgetown Middle School |
| 5 | JR | Clarinet | 08 | Stephen Osaguona | Marrington Middle School |
| 5 | JR | Clarinet | 09 | Mary Cegledy | Waccamaw Middle School |
| 5 | JR | Clarinet | 10 | Lauren Baxter | Ten Oaks Middle School |
| 5 | JR | Clarinet | 11 | Trinity McDavid | Hanahan Middle School |
| 5 | JR | Clarinet | 12 | Lily Ross | Ocean Bay Middle School |
| 5 | JR | Clarinet | 13 | Antanasia Williams | Dillon Middle School |
| 5 | JR | Clarinet | 14 | Corinthian Jackson | Williams Middle School |
| 5 | JR | Clarinet | 15 | Jada Spann | Williams Middle School |
| 5 | JR | Clarinet | 16 | Stephen Carrasco | Ten Oaks Middle School |
| 5 | JR | Clarinet | 17 | Genesis Winquist | Ocean Bay Middle School |
| 5 | JR | Clarinet | 18 | Jasmyne Singleton | R.E. Davis College Preparatory Academy |
| 5 | JR | Clarinet | 19 | Lujaine Kamil | Hanahan Middle School |
| 5 | JR | Clarinet | 20 | Shelby Cox | Socastee Middle School |
| 5 | JR | Clarinet | 21 | Josephine Fletcher | Hanahan Middle School |
| 5 | JR | Clarinet | 22 | Erin Wilson | Georgetown Middle School |
| 5 | JR | Clarinet | 23 | Michelle Do | Hanahan Middle School |
| 5 | JR | Clarinet | 24 | Dara Olufemi | Ocean Bay Middle School |
| 5 | JR | Clarinet | A01 | Jayla Gordon | Southside Middle School |
| 5 | JR | Clarinet | A02 | Lana Mohamed | Hanahan Middle School |
| 5 | JR | Clarinet | A03 | Tristan King | Sangaree Middle School |
| 5 | JR | Clarinet | A04 | Pierson Paul | Waccamaw Middle School |
| 5 | JR | Clarinet | A05 | Maryam Termizi-Abdullah | Socastee Middle School |
| 5 | JR | Clarinet | A06 | Marissa Wear | Ten Oaks Middle School |
| 5 | JR | Clarinet | A07 | Justin Hafner | Daniel Island Middle School |
| 5 | JR | Clarinet | A08 | Rana Mohamed | Hanahan Middle School |
| 5 | JR | Clarinet | A09 | Cassandra Burnett | Sangaree Middle School |
| 5 | JR | Clarinet | A10 | Elya Andrea | St. Anthony Catholic School |
| 5 | JR | Clarinet | A11 | Abigail Ward | Ten Oaks Middle School |
| 5 | JR | Clarinet | A12 | Alleigh Swanson | Hanahan Middle School |
| 5 | JR | Clarinet | A13 | Shakinah Murphy | Dillon Middle School |
| 5 | JR | Clarinet | A14 | Melissa Keene | Ten Oaks Middle School |
| 5 | JR | Clarinet | A15 | Christian Halls | Sangaree Middle School |
| 5 | JR | Clarinet | A16 | Zusette Ramirez | Georgetown Middle School |
| 5 | JR | Clarinet | A17 | Emerson McCraw | Marlboro School of Discovery |
| 5 | JR | Clarinet | A18 | Kanarian Temesgen | Berkley Middle School |
| 5 | JR | Bass Clarinet | 01 | Jaden Kennedy | Ten Oaks Middle School |
| 5 | JR | Bass Clarinet | 02 | Raina Gerald | Loris Middle School |
| 5 | JR | Bass Clarinet | 03 | Benjamin Barker | North Myrtle Beach Middle School |
| 5 | JR | Bass Clarinet | 04 | John Paul Hensley | Ten Oaks Middle School |
| 5 | JR | Bass Clarinet | A01 | Natalie Gnusarev | Ocean Bay Middle School |
| 5 | JR | Bass Clarinet | A02 | Terrika Smalls | Socastee Middle School |
| 5 | JR | Bass Clarinet | A03 | Rieligh Johnson | Hartsville Middle School |
| 5 | JR | Contra Clarinet | 01 | James Collins | Waccamaw Middle School |
| 5 | JR | Contra Clarinet | 02 | Honesty Moore | Dillon Middle School |
| 5 | JR | Alto Sax | 01 | Johnley Gonzales | Long Middle School |
| 5 | JR | Alto Sax | 02 | Alan Rick | Sangaree Middle School |
| 5 | JR | Alto Sax | 03 | Emily Tinnea | Westview Middle School (Goose Creek) |
| 5 | JR | Alto Sax | 04 | Wyatt Lewis | North Myrtle Beach Middle School |
| 5 | JR | Alto Sax | 05 | Connor Truax | Sneed Middle School |
| 5 | JR | Alto Sax | 06 | Isai Rojo-Veyna | Ten Oaks Middle School |
| 5 | JR | Alto Sax | A01 | Ethan Okkerse | Hanahan Middle School |
| 5 | JR | Alto Sax | A02 | Mackenzie Ratliff | Westview Middle School (Goose Creek) |
| 5 | JR | Alto Sax | A03 | Owen Osborne | Marrington Middle School |
| 5 | JR | Alto Sax | A04 | Jeremiah Moore | Alice Drive Middle School |
| 5 | JR | Alto Sax | A05 | Isaac Sanchez | Georgetown Middle School |
| 5 | JR | Tenor Sax | 01 | Juan De La Cruz | Sangaree Middle School |
| 5 | JR | Tenor Sax | 02 | Nicholas Scrio | Cane Bay Middle School |
| 5 | JR | Tenor Sax | A01 | Hunter Quayle | Marrington Middle School |
| 5 | JR | Tenor Sax | A02 | Imani Rugema | Marrington Middle School |
| 5 | JR | Bari Sax | 01 | Hasegawa Laura | Westview Middle School (Goose Creek) |
| 5 | JR | Bari Sax | A01 | William Gregory | Georgetown Middle School |
| 5 | JR | Trumpet | 01 | Dylan Millare | Marrington Middle School |
| 5 | JR | Trumpet | 02 | Ryan Vasquez | Aynor Middle School |
| 5 | JR | Trumpet | 03 | Jer’Mauri Williams | Cane Bay Middle School |
| 5 | JR | Trumpet | 04 | Elizabeth Honeycutt | Waccamaw Middle School |
| 5 | JR | Trumpet | 05 | Simon Felix | Williams Middle School |
| 5 | JR | Trumpet | 06 | Henry Dowe | Ocean Bay Middle School |
| 5 | JR | Trumpet | 07 | Olivia Esaw-Lonzo | Long Middle School |
| 5 | JR | Trumpet | 08 | Andrew Evans | Westview Middle School (Goose Creek) |
| 5 | JR | Trumpet | 09 | Sean Townsend | Marlboro School of Discovery |
| 5 | JR | Trumpet | 10 | Victoria Romero | Myrtle Beach Middle School |
| 5 | JR | Trumpet | 11 | Sincere Carter | Hanahan Middle School |
| 5 | JR | Trumpet | 12 | Jordyn Mihlbauer | Bates Middle School |
| 5 | JR | Trumpet | 13 | Noah Foley | Sangaree Middle School |
| 5 | JR | Trumpet | 14 | Matthew Martin | Georgetown Middle School |
| 5 | JR | Trumpet | 15 | Laken Woodard | Marrington Middle School |
| 5 | JR | Trumpet | 16 | Wesley Ward | Westview Middle School (Goose Creek) |
| 5 | JR | Trumpet | A01 | Budd Trammell | Aynor Middle School |
| 5 | JR | Trumpet | A02 | Cameron Kaye | Aynor Middle School |
| 5 | JR | Trumpet | A03 | Patrick Williams | Ocean Bay Middle School |
| 5 | JR | Trumpet | A04 | Madison Sammons | Sangaree Middle School |
| 5 | JR | Trumpet | A05 | Elijuah Lopez | Williams Middle School |
| 5 | JR | Trumpet | A06 | Taylor Richardson | Georgetown Middle School |
| 5 | JR | Trumpet | A07 | Timothy McInerney | Ten Oaks Middle School |
| 5 | JR | Trumpet | A08 | Fischer Phillips | Waccamaw Middle School |
| 5 | JR | Trumpet | A09 | Andrew Washington | Hanahan Middle School |
| 5 | JR | Trumpet | A10 | Jacob Perdue | Hartsville Middle School |
| 5 | JR | Trumpet | A11 | Dristian Herrera-Diaz | Ten Oaks Middle School |
| 5 | JR | Trumpet | A12 | Lincoln Buxton | Waccamaw Middle School |
| 5 | JR | Horn | 01 | Tilton Carly | St. Anthony Catholic School |
| 5 | JR | Horn | 02 | Bruno D’Ippolito | Ocean Bay Middle School |
| 5 | JR | Horn | 03 | Roni Butbul | Ten Oaks Middle School |
| 5 | JR | Horn | 04 | Niamh Donnelly | Cane Bay Middle School |
| 5 | JR | Horn | 05 | Christian Anderson | Ten Oaks Middle School |
| 5 | JR | Horn | 06 | Evan DeBellis | Hartsville Middle School |
| 5 | JR | Horn | 07 | Matthew Scharnitzky | Daniel Island Middle School |
| 5 | JR | Horn | 08 | Katie Stewart | Hanahan Middle School |
| 5 | JR | Horn | A01 | Molly Stover | Waccamaw Middle School |
| 5 | JR | Horn | A02 | Acaylar Bea | St. Anthony Catholic School |
| 5 | JR | Trombone | 01 | Jake Petersen | Forestbrook Middle School |
| 5 | JR | Trombone | 02 | Paul Kar | Marrington Middle School |
| 5 | JR | Trombone | 03 | Sabrina Wynn | Darlington Middle School |
| 5 | JR | Trombone | 04 | Dominic Smith | Hartsville Middle School |
| 5 | JR | Trombone | 05 | Hadleigh Ortega | Hanahan Middle School |
| 5 | JR | Trombone | 06 | Alex Hairston | Williams Middle School |
| 5 | JR | Trombone | 07 | Jacob Param | Westview Middle School (Goose Creek) |
| 5 | JR | Trombone | 08 | Lily Purdy | Cane Bay Middle School |
| 5 | JR | Trombone | 09 | London Gathers | Westview Middle School (Goose Creek) |
| 5 | JR | Trombone | A01 | Shantanu Chakraborty | Ten Oaks Middle School |
| 5 | JR | Trombone | A02 | Rhett Mullis | Hartsville Middle School |
| 5 | JR | Trombone | A03 | Ross White | Ten Oaks Middle School |
| 5 | JR | Trombone | A04 | Brianna Fisher | Marrington Middle School |
| 5 | JR | Trombone | A05 | Riley Varner | Sangaree Middle School |
| 5 | JR | Trombone | A06 | Jessica Parsley | Philip Simmons Middle School |
| 5 | JR | Trombone | A07 | Sean Smith | Dillon Middle School |
| 5 | JR | Trombone | A08 | Fordham Smith | Daniel Island Middle School |
| 5 | JR | Euphonium | 01 | Jada Griffin | Ten Oaks Middle School |
| 5 | JR | Euphonium | 02 | Nathan Phillips | Ten Oaks Middle School |
| 5 | JR | Euphonium | 03 | Jacob Montroy | Sangaree Middle School |
| 5 | JR | Euphonium | 04 | Rachelle Masse | Sangaree Middle School |
| 5 | JR | Euphonium | A01 | Rha’Nyai Frazier | Dillon Middle School |
| 5 | JR | Euphonium | A02 | Caitlin Adams | Hanahan Middle School |
| 5 | JR | Euphonium | A03 | Mariah Rolle | Marrington Middle School |
| 5 | JR | Tuba | 01 | Jaden Hart | Cane Bay Middle School |
| 5 | JR | Tuba | 02 | Jude Yates | Sneed Middle School |
| 5 | JR | Tuba | 03 | Jose Hernandez | Ten Oaks Middle School |
| 5 | JR | Tuba | 04 | Dominick Hulse | Aynor Middle School |
| 5 | JR | Tuba | 05 | Tamera Benton | Darlington Middle School |
| 5 | JR | Tuba | 06 | Wilson Davenport | Cane Bay Middle School |
| 5 | JR | Tuba | 07 | Chanel Taylor | Philip Simmons Middle School |
| 5 | JR | Tuba | 08 | Kuhn Brett | St. Anthony Catholic School |
| 5 | JR | Tuba | A01 | Gregory Wilson | Williams Middle School |
| 5 | JR | Tuba | A02 | Luke Kibler | Waccamaw Middle School |
| 5 | JR | Tuba | A03 | Jahleel Williams | Bates Middle School |
| 5 | JR | Percussion | 01 | Patrick Cabales | Marrington Middle School |
| 5 | JR | Percussion | 02 | Caleb Harrison | Marrington Middle School |
| 5 | JR | Percussion | 03 | Charlie Millis | Westview Middle School (Goose Creek) |
| 5 | JR | Percussion | 04 | Teondre Smalls | Marrington Middle School |
| 5 | JR | Percussion | 05 | Rylin Thomason | Marrington Middle School |
| 5 | JR | Percussion | 06 | Samuel Downing | Cane Bay Middle School |
| 5 | JR | Percussion | 07 | Kaydence Dougherty | Westview Middle School (Goose Creek) |
| 5 | JR | Percussion | A01 | Jacob Rowell | Cane Bay Middle School |
| 5 | JR | Percussion | A02 | Andrew Scharnitzky | Daniel Island Middle School |
| 5 | JR | Percussion | A03 | Aria Lewis | Hanahan Middle School |
| 5 | JR | Percussion | A04 | Dibby Midgley | Long Middle School |
| 5 | JR | Percussion | A05 | Zachary Hodges | Westview Middle School (Goose Creek) |
| 5 | JR | Percussion | A06 | Jack Penn | Ocean Bay Middle School |
| 5 | JR | Percussion | A07 | Chris Freeman | North Myrtle Beach Middle School |
| 5 | JR | Timpani | 01 | Isaiah Moro | Ocean Bay Middle School |
| 5 | JR | Timpani | A01 | Shockey Ava | St. Anthony Catholic School |