| Region | Level | Instrument | Chair | Name | School |
| 5 | SR | Flute | 01 | Sydney Garver | Saint James High School |
| 5 | SR | Flute | 02 | Omari Robinson | Cane Bay High School |
| 5 | SR | Flute | 03 | Isaque Da Costa | Stratford High School |
| 5 | SR | Flute | 04 | Benjamin Dameron | Saint James High School |
| 5 | SR | Flute | 05 | Jakierah Eagle | Dillon High School |
| 5 | SR | Flute | 06 | Sam Senthil | S.C. Governor’s School for Science & Mathematics |
| 5 | SR | Flute | 07 | Emma Ryen | Carolina Forest High School |
| 5 | SR | Flute | 08 | Emily Moore | Goose Creek High School |
| 5 | SR | Flute | 09 | Genesis Gooden | Wilson High School |
| 5 | SR | Flute | 10 | Aathmika Srinivasaprabu | S.C. Governor’s School for Science & Mathematics |
| 5 | SR | Flute | 11 | Bridget Joyner | Stratford High School |
| 5 | SR | Flute | 12 | Jairo Ramos de la Cruz | Waccamaw High School |
| 5 | SR | Flute | A1 | Rachel Collins | Stratford High School |
| 5 | SR | Flute | A2 | Katelynn Shelley | West Florence High School |
| 5 | SR | Flute | A3 | Shanese Malicad | Stratford High School |
| 5 | SR | Flute | A4 | Naomi Reed | Georgetown High School |
| 5 | SR | Flute | A5 | Mackenzie Johnson | Stratford High School |
| 5 | SR | Flute | A6 | Lydia Rhodes | West Florence High School |
| 5 | SR | Oboe | 01 | Hope Holmes | Hanahan High School |
| 5 | SR | Oboe | 02 | Ava Thompson | Cane Bay High School |
| 5 | SR | Bassoon | 01 | Dylan Massey | Hanahan High School |
| 5 | SR | Bassoon | 02 | Bryce Hatfield | Stratford High School |
| 5 | SR | Bassoon | 03 | Asa Astacio | Hanahan High School |
| 5 | SR | Bassoon | 04 | Kolten Oeller | Berkeley High School |
| 5 | SR | Bassoon | A1 | Aiden Klepper | Saint James High School |
| 5 | SR | Clarinet | 01 | Anna Baumgarner | Stratford High School |
| 5 | SR | Clarinet | 02 | Shanya Blanchard | Goose Creek High School |
| 5 | SR | Clarinet | 03 | Candice Taylor | Hanahan High School |
| 5 | SR | Clarinet | 04 | Jayla Kennedy-Blue | Wilson High School |
| 5 | SR | Clarinet | 05 | Kailyn Haferl | Carolina Forest High School |
| 5 | SR | Clarinet | 06 | Tristan Thompson | Cane Bay High School |
| 5 | SR | Clarinet | 07 | Sanaa Griffin | Wilson High School |
| 5 | SR | Clarinet | 08 | Margaux Judy | Conway High School |
| 5 | SR | Clarinet | 09 | William Owen | North Myrtle Beach High School |
| 5 | SR | Clarinet | 10 | Colin Nichols | Hanahan High School |
| 5 | SR | Clarinet | 11 | Kohlton Rosati | North Myrtle Beach High School |
| 5 | SR | Clarinet | 12 | Daniel Silva | Cane Bay High School |
| 5 | SR | Clarinet | 13 | Mary Ella Grier | West Florence High School |
| 5 | SR | Clarinet | 14 | Ivalee Polk | Berkeley High School |
| 5 | SR | Clarinet | 15 | Saona Collins | Central High School |
| 5 | SR | Clarinet | 16 | Kenlei McQueen-Wells | Goose Creek High School |
| 5 | SR | Clarinet | 17 | Elijah Mills | Stratford High School |
| 5 | SR | Clarinet | 18 | Caydence Storey | South Florence High School |
| 5 | SR | Clarinet | 19 | Savannah Long | Loris High School |
| 5 | SR | Clarinet | 20 | Rhys Hollifield | West Florence High School |
| 5 | SR | Clarinet | 21 | Abril Alvarez | Hanahan High School |
| 5 | SR | Clarinet | 22 | Jenna Benkert | Saint James High School |
| 5 | SR | Clarinet | 23 | Dominic Troutman | Stratford High School |
| 5 | SR | Clarinet | 24 | Robert Ballares | Cane Bay High School |
| 5 | SR | Clarinet | A1 | Tanna Adams | Chesterfield High School |
| 5 | SR | Clarinet | A2 | Annabella Becker | Cane Bay High School |
| 5 | SR | Clarinet | A3 | Matthew Slade | S.C. Governor’s School for Science & Mathematics |
| 5 | SR | Clarinet | A4 | Stephanie Gunnells | Goose Creek High School |
| 5 | SR | Clarinet | A5 | Branton Ciuffetelli | Georgetown High School |
| 5 | SR | Clarinet | A6 | A’niya Witherspoon | Goose Creek High School |
| 5 | SR | Clarinet | A7 | Sereniti Davis-McLeod | Dillon High School |
| 5 | SR | Clarinet | A8 | Abigail Dukes | Waccamaw High School |
| 5 | SR | Bass Clarinet | 01 | Monica Jackson | Sumter High School |
| 5 | SR | Bass Clarinet | 02 | Danielle Greene | Goose Creek High School |
| 5 | SR | Bass Clarinet | 03 | Angel Hardwick | Hanahan High School |
| 5 | SR | Bass Clarinet | 04 | Ayden Agee | Cane Bay High School |
| 5 | SR | Bass Clarinet | A1 | Stary Samuel | Wilson High School |
| 5 | SR | Contra Clarinet | 01 | Shayla Downing | Dillon High School |
| 5 | SR | Contra Clarinet | 02 | Daniel Galvagni | Philip Simmons High School |
| 5 | SR | Alto Sax | 01 | Alejandro Athearn | Cane Bay High School |
| 5 | SR | Alto Sax | 02 | Robert Dorman | Saint James High School |
| 5 | SR | Alto Sax | 03 | Caden Causey | West Florence High School |
| 5 | SR | Alto Sax | 04 | Breydon Woods | Carolina Forest High School |
| 5 | SR | Alto Sax | 05 | Elvis Flores | Stratford High School |
| 5 | SR | Alto Sax | 06 | Logan Johnson | Stratford High School |
| 5 | SR | Alto Sax | 07 | Dylan Jenks | Saint James High School |
| 5 | SR | Alto Sax | 08 | Kris McGee | Stratford High School |
| 5 | SR | Alto Sax | A1 | Abram McDuffie | Sumter High School |
| 5 | SR | Alto Sax | A2 | Levi Ferrara | Hanahan High School |
| 5 | SR | Alto Sax | A3 | Chasey Falat | Cane Bay High School |
| 5 | SR | Tenor Sax | 01 | Cincere Covington | Marlboro County High School |
| 5 | SR | Tenor Sax | 02 | JahZara Wilder | West Florence High School |
| 5 | SR | Tenor Sax | 03 | Jordan Bray | Socastee High School |
| 5 | SR | Tenor Sax | 04 | Jada Jenkins | Cane Bay High School |
| 5 | SR | Tenor Sax | A1 | Tiffany Funderburk | Central High School |
| 5 | SR | Bari Sax | 01 | William Suggs | Stratford High School |
| 5 | SR | Bari Sax | 02 | Helen Jordan | Goose Creek High School |
| 5 | SR | Bari Sax | A1 | Legend Quick | Marlboro County High School |
| 5 | SR | Trumpet | 01 | Preston Figueras | West Florence High School |
| 5 | SR | Trumpet | 02 | Alexander Orihuela | Goose Creek High School |
| 5 | SR | Trumpet | 03 | Angello Gonzalez | Cane Bay High School |
| 5 | SR | Trumpet | 04 | Ajay Cullen | Socastee High School |
| 5 | SR | Trumpet | 05 | Bryan Garcia-Romero | Goose Creek High School |
| 5 | SR | Trumpet | 06 | Jackson Tucker | Stratford High School |
| 5 | SR | Trumpet | 07 | Ivan Morely | Marion High School |
| 5 | SR | Trumpet | 08 | Gabbrielle Mitchell | Hanahan High School |
| 5 | SR | Trumpet | 09 | Xander Brooks | Sumter High School |
| 5 | SR | Trumpet | 10 | Lauren Tinnea | Stratford High School |
| 5 | SR | Trumpet | 11 | Hannah Quindo | Hanahan High School |
| 5 | SR | Trumpet | 12 | David Ni | Cane Bay High School |
| 5 | SR | Trumpet | 13 | Sydney Brooks | Hanahan High School |
| 5 | SR | Trumpet | 14 | Cameron Ellison | Dillon High School |
| 5 | SR | Trumpet | 15 | Brianna Chrzanowski | West Florence High School |
| 5 | SR | Trumpet | 16 | Abygail Walton | Carolina Forest High School |
| 5 | SR | Trumpet | A1 | Austin Vierthaler | Berkeley High School |
| 5 | SR | Trumpet | A2 | Trent’n Chinners | Stratford High School |
| 5 | SR | Trumpet | A3 | John Perez-Alfonso | Loris High School |
| 5 | SR | Trumpet | A4 | Caio Andrecioli | Cheraw High School |
| 5 | SR | Trumpet | A5 | Austin Brown | McBee High School |
| 5 | SR | Trumpet | A6 | Eli Russell | Hartsville High School |
| 5 | SR | Trumpet | A7 | Thomas Kyne | Carolina Forest High School |
| 5 | SR | Trumpet | A8 | Noah Huffman | Cane Bay High School |
| 5 | SR | Horn | 01 | Geogia Hand | Carolina Forest High School |
| 5 | SR | Horn | 02 | William Pirkle | West Florence High School |
| 5 | SR | Horn | 03 | Henry Odgers | Stratford High School |
| 5 | SR | Horn | 04 | Brayden Stillwagon | Carolina Forest High School |
| 5 | SR | Horn | 05 | Sophia Andreski | S.C. Governor’s School for Science & Mathematics |
| 5 | SR | Horn | 06 | Jonathan Ursits | Socastee High School |
| 5 | SR | Horn | 07 | Milo Smith | Stratford High School |
| 5 | SR | Horn | 08 | Kristina Mims | Carolina Forest High School |
| 5 | SR | Horn | A1 | Lauren Postell | Stratford High School |
| 5 | SR | Horn | A2 | Jake Heldreth | Aynor High School |
| 5 | SR | Horn | A3 | Lena Rafferty | Hanahan High School |
| 5 | SR | Horn | A4 | Jay Wigfall | Stratford High School |
| 5 | SR | Trombone | 01 | Dominic Rugema | Goose Creek High School |
| 5 | SR | Trombone | 02 | Luca Mastroianni | S.C. Governor’s School for Science & Mathematics |
| 5 | SR | Trombone | 03 | Lily Collazo | Goose Creek High School |
| 5 | SR | Trombone | 04 | Keandre Ham | Wilson High School |
| 5 | SR | Trombone | 05 | Lana Ames | Stratford High School |
| 5 | SR | Trombone | 06 | Arianna Solorio | Stratford High School |
| 5 | SR | Trombone | 07 | Sam Cott | Hanahan High School |
| 5 | SR | Trombone | 08 | Subee Vongsavanh | Carolina Forest High School |
| 5 | SR | Trombone | 09 | Sunny Armstrong | Stratford High School |
| 5 | SR | Trombone | A1 | Robinson Mendez | Aynor High School |
| 5 | SR | Trombone | A2 | Morris Cooper | West Florence High School |
| 5 | SR | Trombone | A3 | Olivia Dang | Berkeley High School |
| 5 | SR | Trombone | A4 | Mia Attar | Cane Bay High School |
| 5 | SR | Trombone | A5 | Zora Bradley | Sumter High School |
| 5 | SR | Euphonium | 01 | Andrew Ferreira | Saint James High School |
| 5 | SR | Euphonium | 02 | Ryan Preciado | Carolina Forest High School |
| 5 | SR | Euphonium | 03 | Gwyn Meador | Cane Bay High School |
| 5 | SR | Euphonium | 04 | Osman Nieto Lopez | Goose Creek High School |
| 5 | SR | Euphonium | A1 | Luke Wooten | Stratford High School |
| 5 | SR | Euphonium | A2 | Samantha Murphy | West Florence High School |
| 5 | SR | Tuba | 01 | Joelie Propst | Saint James High School |
| 5 | SR | Tuba | 02 | Christopher Bess | Darlington High School |
| 5 | SR | Tuba | 03 | Jovon Cauthen | West Florence High School |
| 5 | SR | Tuba | 04 | Erik Ortuno-Martinez | Stratford High School |
| 5 | SR | Tuba | 05 | Aaliyah Young | Stratford High School |
| 5 | SR | Tuba | 06 | Declan Hawthorne | Stratford High School |
| 5 | SR | Tuba | 07 | Bishop Henderson | Carolina Forest High School |
| 5 | SR | Tuba | 08 | Kayson Capazzi | Goose Creek High School |
| 5 | SR | Tuba | A1 | Jeremiah McCray | Goose Creek High School |
| 5 | SR | Tuba | A2 | Gabriel Stanley | Dillon High School |
| 5 | SR | Tuba | A3 | Jaiden Boone | Timberland High School |
| 5 | SR | Tuba | A4 | Jerry Cochran | Stratford High School |
| 5 | SR | Bass Trombone | 01 | Jabari Wilson | West Florence High School |
| 5 | SR | Bass Trombone | A1 | William Christian | Carolina Forest High School |
| 5 | SR | Percussion | 01 | Luke Russell | Stratford High School |
| 5 | SR | Percussion | 02 | Zoie Cid | Stratford High School |
| 5 | SR | Percussion | 03 | Naomi Driskell | Hanahan High School |
| 5 | SR | Percussion | 04 | Aydan Moore | Cane Bay High School |
| 5 | SR | Percussion | 05 | Freddy Pleis | Stratford High School |
| 5 | SR | Percussion | 06 | Solomon Smith | Hanahan High School |
| 5 | SR | Percussion | 07 | Trevor Carter | North Myrtle Beach High School |
| 5 | SR | Percussion | A1 | Zack Safa | Stratford High School |
| 5 | SR | Percussion | A2 | Landon Mula | Socastee High School |
| 5 | SR | Percussion | A3 | Charles Hauck | Stratford High School |
| 5 | SR | Percussion | A4 | West Boyd | Hanahan High School |
| 5 | SR | Timpani | 01 | Ryan Carswell | Philip Simmons High School |
| 5 | SR | Timpani | A1 | Joshua McNeil | West Florence High School |