| Region | Level | Instrument | Region Chair | Name | School |
| 6 | CL | Flute | 01 | Audrey McGurk | Clover High School |
| 6 | CL | Flute | 02 | Erin McCallion | Woodruff High School |
| 6 | CL | Flute | 03 | Darya Sarioglo | James F. Byrnes High School |
| 6 | CL | Flute | 04 | Layla Mitchell | Spartanburg High School |
| 6 | CL | Flute | 05 | Finley Wine | Clover High School |
| 6 | CL | Flute | 06 | Clayton Holmes | Spartanburg High School |
| 6 | CL | Flute | 07 | Anjali Perera | Dorman High School |
| 6 | CL | Flute | 08 | Paige Rapley | James F. Byrnes High School |
| 6 | CL | Flute | 09 | Kaiwen Ye | Dorman High School |
| 6 | CL | Flute | 10 | Aaliyah Martinez | James F. Byrnes High School |
| 6 | CL | Flute | 11 | Amy Ramirez | Dorman High School |
| 6 | CL | Flute | 12 | Ashley Castillo-Lopez | Dorman High School |
| 6 | CL | Flute | A01 | Ashlyn Terry | Clover High School |
| 6 | CL | Flute | A02 | Danielle Weber | Dorman High School |
| 6 | CL | Flute | A03 | Kelsey Adams | James F. Byrnes High School |
| 6 | CL | Flute | A04 | Charlee Laws | Clover High School |
| 6 | CL | Flute | A05 | Gabrielle Miller | Clover High School |
| 6 | CL | Flute | A06 | Nyla Pinckney | James F. Byrnes High School |
| 6 | CL | Oboe | 01 | Jacob Herbert | Boiling Springs High School |
| 6 | CL | Oboe | 02 | Maddie Hatchett | Dorman High School |
| 6 | CL | Oboe | 03 | Sam Van Hyning | Spartanburg High School |
| 6 | CL | Oboe | 04 | Cadence Dismukes | James F. Byrnes High School |
| 6 | CL | Oboe | A01 | Jackson Brown | Boiling Springs High School |
| 6 | CL | Bassoon | 01 | Karly Hough | James F. Byrnes High School |
| 6 | CL | Bassoon | 02 | Austyn Turley | Dorman High School |
| 6 | CL | Clarinet | 01 | Adian Ahern | Spartanburg High School |
| 6 | CL | Clarinet | 02 | Alex Amezcua | York Comprehensive High School |
| 6 | CL | Clarinet | 03 | Lauren Burger | James F. Byrnes High School |
| 6 | CL | Clarinet | 04 | Dylan Prus | Spartanburg High School |
| 6 | CL | Clarinet | 05 | Shelby Stewart | York Comprehensive High School |
| 6 | CL | Clarinet | 06 | Lanie Budnick | James F. Byrnes High School |
| 6 | CL | Clarinet | 07 | Rylee Scott | James F. Byrnes High School |
| 6 | CL | Clarinet | 08 | Elise Jennemann | James F. Byrnes High School |
| 6 | CL | Clarinet | 09 | Emerie West | Boiling Springs High School |
| 6 | CL | Clarinet | 10 | Kiara Booker | James F. Byrnes High School |
| 6 | CL | Clarinet | 11 | Claire Hammond | Spartanburg High School |
| 6 | CL | Clarinet | 12 | Lily Smith | Spartanburg High School |
| 6 | CL | Clarinet | 13 | Taylor Hicks | Boiling Springs High School |
| 6 | CL | Clarinet | 14 | Anne Ramella | James F. Byrnes High School |
| 6 | CL | Clarinet | 15 | Gabriela Tilley | Chesnee High School |
| 6 | CL | Clarinet | 16 | Clarissa Kristjanson | Clover High School |
| 6 | CL | Clarinet | 17 | Beth Mize | Boiling Springs High School |
| 6 | CL | Clarinet | 18 | Abigail Smith | Chapman High School |
| 6 | CL | Clarinet | 19 | Christopher Hansen | Clover High School |
| 6 | CL | Clarinet | 20 | Jennifer McIlwain | James F. Byrnes High School |
| 6 | CL | Clarinet | 21 | Alex Edwards | Boiling Springs High School |
| 6 | CL | Clarinet | 22 | Jayln Keating-Powers | Clover High School |
| 6 | CL | Clarinet | 23 | Ivy Chen | Blacksburg High School |
| 6 | CL | Clarinet | 24 | Miranda Alexander | Clover High School |
| 6 | CL | Clarinet | A01 | Kalie DeSherlia | Dorman High School |
| 6 | CL | Clarinet | A02 | Danica Harmon | Dorman High School |
| 6 | CL | Clarinet | A03 | Eli Lor | Dorman High School |
| 6 | CL | Clarinet | A04 | Mya Ferguson | Spartanburg Day School |
| 6 | CL | Clarinet | A05 | Isabella Martinez | Chapman High School |
| 6 | CL | Clarinet | A06 | Destiny Drummond | Dorman High School |
| 6 | CL | Clarinet | A07 | Axel Paz | York Comprehensive High School |
| 6 | CL | Clarinet | A08 | Veronica Montgomery | Boiling Springs High School |
| 6 | CL | Bass Clarinet | 01 | Alyssa Thompson | James F. Byrnes High School |
| 6 | CL | Bass Clarinet | 02 | Mickey Harmon | Gaffney Senior High School |
| 6 | CL | Alto Sax | 01 | Nathan Jones | James F. Byrnes High School |
| 6 | CL | Alto Sax | 02 | Gianni Allen | Clover High School |
| 6 | CL | Alto Sax | 03 | Maxwell Bolds | James F. Byrnes High School |
| 6 | CL | Alto Sax | 04 | Sarah Hicks | Mid-Carolina High School |
| 6 | CL | Alto Sax | 05 | Brett Menz | Clover High School |
| 6 | CL | Alto Sax | 06 | Gavin Monaghan | Clover High School |
| 6 | CL | Alto Sax | A01 | Riley Miller-King | Dorman High School |
| 6 | CL | Alto Sax | A02 | Fletcher Martin | James F. Byrnes High School |
| 6 | CL | Alto Sax | A03 | Jaquori Peters | James F. Byrnes High School |
| 6 | CL | Tenor Sax | 01 | Evan Beasley | James F. Byrnes High School |
| 6 | CL | Tenor Sax | 02 | Charles Loop | Landrum High School |
| 6 | CL | Bari Sax | 01 | Max Cash | Spartanburg High School |
| 6 | CL | Bari Sax | A01 | Dell Brockman | Woodruff High School |
| 6 | CL | Trumpet | 01 | Eli Watson | James F. Byrnes High School |
| 6 | CL | Trumpet | 02 | Gavin Turner | York Comprehensive High School |
| 6 | CL | Trumpet | 03 | Keenan Foster | James F. Byrnes High School |
| 6 | CL | Trumpet | 04 | Isaac Moroz | York Comprehensive High School |
| 6 | CL | Trumpet | 05 | Elijah Wiley | Spartanburg Christian Academy |
| 6 | CL | Trumpet | 06 | Edward Konyrev | Boiling Springs High School |
| 6 | CL | Trumpet | 07 | Dillon Doubledee | Clover High School |
| 6 | CL | Trumpet | 08 | Emma Appleyard | Clover High School |
| 6 | CL | Trumpet | 09 | Carter Presley | James F. Byrnes High School |
| 6 | CL | Trumpet | 10 | Ian Kimbrell | Boiling Springs High School |
| 6 | CL | Trumpet | 11 | Arelimar Colon | Gaffney Senior High School |
| 6 | CL | Trumpet | 12 | Ethan Ni | James F. Byrnes High School |
| 6 | CL | Trumpet | 13 | Juan Martinez | James F. Byrnes High School |
| 6 | CL | Trumpet | 14 | Austin Brewer | Clover High School |
| 6 | CL | Trumpet | 15 | Clark Bailey | Boiling Springs High School |
| 6 | CL | Trumpet | 16 | Nick Mitchell | James F. Byrnes High School |
| 6 | CL | Trumpet | A01 | Chandler Jenkins | Dorman High School |
| 6 | CL | Trumpet | A02 | Trey Pannier | Newberry High School |
| 6 | CL | Trumpet | A03 | Hunter Briles | Boiling Springs High School |
| 6 | CL | Trumpet | A04 | Alex Montoya | James F. Byrnes High School |
| 6 | CL | Trumpet | A05 | Karina Lopez-Campos | Woodruff High School |
| 6 | CL | Trumpet | A06 | Dylan Diaz | Boiling Springs High School |
| 6 | CL | Trumpet | A07 | Lauren Patterson | Spartanburg High School |
| 6 | CL | Trumpet | A08 | Steven Egge | Spartanburg High School |
| 6 | CL | Horn | 01 | Parker Hoenig | Dorman High School |
| 6 | CL | Horn | 02 | Hailey Stribble | James F. Byrnes High School |
| 6 | CL | Horn | 03 | Vanessa Cholak | Chesnee High School |
| 6 | CL | Horn | 04 | Rachel Owensby | Spartanburg High School |
| 6 | CL | Horn | 05 | Henriette Brenner | James F. Byrnes High School |
| 6 | CL | Horn | 06 | Emily Buell | Broome High School |
| 6 | CL | Horn | 07 | Grace Bohmer | James F. Byrnes High School |
| 6 | CL | Horn | 08 | James Bright | Spartanburg High School |
| 6 | CL | Horn | A01 | Anna Pettit | High Point Academy |
| 6 | CL | Horn | A02 | Colin Linaman | James F. Byrnes High School |
| 6 | CL | Horn | A03 | Ethan Fenske | Clover High School |
| 6 | CL | Horn | A04 | Aidan Kenny | Boiling Springs High School |
| 6 | CL | Trombone | 01 | Tenia Evans | Dorman High School |
| 6 | CL | Trombone | 02 | Braden Baucan | Dorman High School |
| 6 | CL | Trombone | 03 | Nolin Nichols | York Comprehensive High School |
| 6 | CL | Trombone | 04 | Ben Kaltenbach | Clover High School |
| 6 | CL | Trombone | 05 | Jesus Ponce | Chesnee High School |
| 6 | CL | Trombone | 06 | Darius Prim | James F. Byrnes High School |
| 6 | CL | Trombone | 07 | Isaac McLeod | Boiling Springs High School |
| 6 | CL | Trombone | 08 | Jackson Lewis | Clover High School |
| 6 | CL | Trombone | 09 | Douglas Patterson | York Comprehensive High School |
| 6 | CL | Trombone | A01 | Kalli Faulkner | Dorman High School |
| 6 | CL | Trombone | A02 | Chase Wagner | Clover High School |
| 6 | CL | Trombone | A03 | Brandon Rudy | Clover High School |
| 6 | CL | Trombone | A04 | TJ Pack | Chapman High School |
| 6 | CL | Trombone | A05 | Gwen Norris | Woodruff High School |
| 6 | CL | Euphonium | 01 | Presley Orr | James F. Byrnes High School |
| 6 | CL | Euphonium | 02 | Jackson Sistrunk | James F. Byrnes High School |
| 6 | CL | Euphonium | 03 | James Jean-Louis | Union County High School |
| 6 | CL | Euphonium | 04 | Logan Chapman | Boiling Springs High School |
| 6 | CL | Euphonium | A01 | Kaleb Thomas | Woodruff High School |
| 6 | CL | Euphonium | A02 | Gabe Chabre | James F. Byrnes High School |
| 6 | CL | Tuba | 01 | Miles Brooks | Dorman High School |
| 6 | CL | Tuba | 02 | Meredith Sparks | Boiling Springs High School |
| 6 | CL | Tuba | 03 | Ryan Cook | James F. Byrnes High School |
| 6 | CL | Tuba | 04 | Zee Moss | James F. Byrnes High School |
| 6 | CL | Tuba | 05 | Domenick Rogers-Serrano | York Comprehensive High School |
| 6 | CL | Tuba | 06 | Destiny Hines | Boiling Springs High School |
| 6 | CL | Tuba | 07 | Jack Taylor | Spartanburg High School |
| 6 | CL | Tuba | 08 | Mason Barath | James F. Byrnes High School |
| 6 | CL | Tuba | A01 | Trent Burton | Clover High School |
| 6 | CL | Tuba | A02 | Kylie Fravel | Boiling Springs High School |
| 6 | CL | Tuba | A03 | Caitlyn Eigner | James F. Byrnes High School |
| 6 | CL | Tuba | A04 | Samuel Bonneval | James F. Byrnes High School |
| 6 | CL | Bass Trombone | 01 | Ryan Self | Laurens District 55 High School |
| 6 | CL | Bass Trombone | A01 | Aaron Hair | Dorman High School |
| 6 | CL | Percussion | 01 | Jackson Hall | Spartanburg High School |
| 6 | CL | Percussion | 02 | Kristian Echols | Dorman High School |
| 6 | CL | Percussion | 03 | Riley McDonald | James F. Byrnes High School |
| 6 | CL | Percussion | 04 | Corban Vander Ploeg | James F. Byrnes High School |
| 6 | CL | Percussion | 05 | Isaac Dobson | James F. Byrnes High School |
| 6 | CL | Percussion | 06 | Grady McCullough | Broome High School |
| 6 | CL | Percussion | 07 | Jackson Demumbreum | James F. Byrnes High School |
| 6 | CL | Percussion | A01 | Logan Smith | Clover High School |
| 6 | CL | Percussion | A02 | Sawyer Spearman | Clover High School |
| 6 | CL | Percussion | A03 | Noah Broadwell | York Comprehensive High School |
| 6 | CL | Percussion | A04 | Tyler Case | Dorman High School |
| 6 | CL | Timpani | 1 | Brian Scott | Laurens District 55 High School |
| 6 | CL | Timpani | A01 | Malachi Watts | Spartanburg High School |