| Region | Level | Instrument | Chair | Name | School |
| 6 | SR | Flute | 01 | Hannah Wodecki | Clover High School |
| 6 | SR | Flute | 02 | Hayley Cantrell | Dorman High School |
| 6 | SR | Flute | 03 | Claudia Comer | Boiling Springs High School |
| 6 | SR | Flute | 04 | Kathy Ramirez | Boiling Springs High School |
| 6 | SR | Flute | 05 | Lucia Gaitan | Mid-Carolina High School |
| 6 | SR | Flute | 06 | Jenna Figureiredo | James F. Byrnes High School |
| 6 | SR | Flute | 07 | Emily Clark | Dorman High School |
| 6 | SR | Flute | 08 | Haylen Satterfield | Dorman High School |
| 6 | SR | Flute | 09 | Wallace Chapman | Spartanburg Day School |
| 6 | SR | Flute | 10 | Kaley McMillan | James F. Byrnes High School |
| 6 | SR | Flute | 11 | Miranda Robinson | Clover High School |
| 6 | SR | Flute | 12 | Abby Bowen | York Comprehensive High School |
| 6 | SR | Flute | A01 | Abby Palmer | York Comprehensive High School |
| 6 | SR | Flute | A02 | Daryl-Brooke Kirby | Blacksburg High School |
| 6 | SR | Flute | A03 | Kailey Love | James F. Byrnes High School |
| 6 | SR | Flute | A04 | Raegan Welch | James F. Byrnes High School |
| 6 | SR | Flute | A05 | Erin Durflinger | York Comprehensive High School |
| 6 | SR | Flute | A06 | Jennifer Arteaga | Boiling Springs High School |
| 6 | SR | Oboe | 01 | Chase Ethridge | James F. Byrnes High School |
| 6 | SR | Oboe | 02 | Ellie Vensel | Spartanburg High School |
| 6 | SR | Oboe | 03 | Liz Dillard | Boiling Springs High School |
| 6 | SR | Oboe | 04 | Kelly Thao | York Comprehensive High School |
| 6 | SR | Bassoon | 01 | Hunter Lanier | Blacksburg High School |
| 6 | SR | Bassoon | 02 | Tashler Greene | Spartanburg Day School |
| 6 | SR | Bassoon | 03 | Bishop Nodine | Boiling Springs High School |
| 6 | SR | Bassoon | 04 | Paige Moroz | York Comprehensive High School |
| 6 | SR | Clarinet | 01 | Caitlin Roberson | James F. Byrnes High School |
| 6 | SR | Clarinet | 02 | Sophie Smiley | York Comprehensive High School |
| 6 | SR | Clarinet | 03 | Kylan Hayes | Dorman High School |
| 6 | SR | Clarinet | 04 | Christina Evans | Boiling Springs High School |
| 6 | SR | Clarinet | 05 | Daria Jackson | Clover High School |
| 6 | SR | Clarinet | 06 | Carley Willis | James F. Byrnes High School |
| 6 | SR | Clarinet | 07 | Kara Thornton | Dorman High School |
| 6 | SR | Clarinet | 08 | Marcel Burgess | Dorman High School |
| 6 | SR | Clarinet | 09 | MacKenzie Dragun | Clover High School |
| 6 | SR | Clarinet | 10 | Emma Sisk | Chapman High School |
| 6 | SR | Clarinet | 11 | Sara Brown | James F. Byrnes High School |
| 6 | SR | Clarinet | 12 | Madison Oviedo | Mid-Carolina High School |
| 6 | SR | Clarinet | 13 | Tyller Bowling | James F. Byrnes High School |
| 6 | SR | Clarinet | 14 | Molly Quetel | Clover High School |
| 6 | SR | Clarinet | 15 | DeAnn Conley | Dorman High School |
| 6 | SR | Clarinet | 16 | Breanna Weber | James F. Byrnes High School |
| 6 | SR | Clarinet | 17 | Rachel Summers | Spartanburg Day School |
| 6 | SR | Clarinet | 18 | Jack Graham | Spartanburg High School |
| 6 | SR | Clarinet | 19 | Sophie Lyczek | Boiling Springs High School |
| 6 | SR | Clarinet | 20 | Mallory Tutterrow | Boiling Springs High School |
| 6 | SR | Clarinet | 21 | Muslimah Muhammad | James F. Byrnes High School |
| 6 | SR | Clarinet | 22 | Tori Melton | James F. Byrnes High School |
| 6 | SR | Clarinet | 23 | Brooklyn Clive | Blacksburg High School |
| 6 | SR | Bass Clarinet | 01 | Colby Hermansen | Clover High School |
| 6 | SR | Bass Clarinet | 02 | Bethanie Murriel | Chapman High School |
| 6 | SR | Bass Clarinet | 03 | Ronan Sanchez | Newberry High School |
| 6 | SR | Contra Clarinet | 01 | Cyan Mayfield | York Comprehensive High School |
| 6 | SR | Alto Sax | 01 | Thomas Scholz | James F. Byrnes High School |
| 6 | SR | Alto Sax | 02 | Abby Traylor | York Comprehensive High School |
| 6 | SR | Alto Sax | 03 | Zeke Walsh | Boiling Springs High School |
| 6 | SR | Alto Sax | 04 | Alex Weygandt | Spartanburg High School |
| 6 | SR | Alto Sax | 05 | Victoria Koons | Chapman High School |
| 6 | SR | Alto Sax | 06 | Auburn Collins | James F. Byrnes High School |
| 6 | SR | Alto Sax | A01 | Sloane Hiller | Clover High School |
| 6 | SR | Alto Sax | A02 | Chad Frost | Spartanburg Day School |
| 6 | SR | Alto Sax | A03 | Evelyn Stephens | Spartanburg High School |
| 6 | SR | Tenor Sax | 01 | Will Mcdonald | James F. Byrnes High School |
| 6 | SR | Tenor Sax | 02 | Elisabeth Miranda | Gaffney Senior High School |
| 6 | SR | Tenor Sax | A01 | James Corbin | Spartanburg High School |
| 6 | SR | Bari Sax | 01 | Clayton Gibson | Chesnee High School |
| 6 | SR | Bari Sax | A01 | Wesley Bagwell | York Comprehensive High School |
| 6 | SR | Trumpet | 01 | Charlie Gibson | Clover High School |
| 6 | SR | Trumpet | 02 | Avery Transiskus | Spartanburg High School |
| 6 | SR | Trumpet | 03 | Jaime Lagos | Dorman High School |
| 6 | SR | Trumpet | 04 | Andrew Brown | Boiling Springs High School |
| 6 | SR | Trumpet | 05 | Colin Murphy | Dorman High School |
| 6 | SR | Trumpet | 06 | Connor Hammond | Spartanburg Day School |
| 6 | SR | Trumpet | 07 | Trevor Stevens | Clover High School |
| 6 | SR | Trumpet | 08 | Jonathan Wright | James F. Byrnes High School |
| 6 | SR | Trumpet | 09 | Bailey Arena | Boiling Springs High School |
| 6 | SR | Trumpet | 10 | Madison Garner | James F. Byrnes High School |
| 6 | SR | Trumpet | 11 | Declan Cahill | Clover High School |
| 6 | SR | Trumpet | 12 | Andy Bogan | Spartanburg High School |
| 6 | SR | Trumpet | 13 | Alex Schreiter | James F. Byrnes High School |
| 6 | SR | Trumpet | 14 | Garrett Pemberton | James F. Byrnes High School |
| 6 | SR | Trumpet | 15 | McKenzie Applegate | York Comprehensive High School |
| 6 | SR | Trumpet | 16 | Mark Wells | Mid-Carolina High School |
| 6 | SR | Trumpet | A01 | Colin Wilkie | Boiling Springs High School |
| 6 | SR | Trumpet | A02 | Joe Murray | Mid-Carolina High School |
| 6 | SR | Trumpet | A03 | Mickenna Younker | Chapman High School |
| 6 | SR | Trumpet | A04 | Paul Owen | Boiling Springs High School |
| 6 | SR | Trumpet | A05 | Marilyn Turner | Blacksburg High School |
| 6 | SR | Trumpet | A06 | Davin Lor | Dorman High School |
| 6 | SR | Trumpet | A07 | Skylar Starnes | Gaffney Senior High School |
| 6 | SR | Trumpet | A08 | Enajah McCluney | Chapman High School |
| 6 | SR | Horn | 01 | Isaiah Adderholdt | S.C. Governor’s School for the Arts and Humanities – REGION 6 |
| 6 | SR | Horn | 02 | Lauren Sellars | Boiling Springs High School |
| 6 | SR | Horn | 03 | Isaiah Colon | Dorman High School |
| 6 | SR | Horn | 04 | Nathan Jones | Spartanburg High School |
| 6 | SR | Horn | 05 | Chancellor Roark | Dorman High School |
| 6 | SR | Horn | 06 | Matthew Jones | Dorman High School |
| 6 | SR | Horn | 07 | Emily Moorhouse | James F. Byrnes High School |
| 6 | SR | Horn | 08 | Samuel Lominick | Newberry High School |
| 6 | SR | Horn | A01 | Hailey Lyons | Chapman High School |
| 6 | SR | Horn | A02 | Drew Joyce | Spartanburg High School |
| 6 | SR | Horn | A03 | Christopher DeWine | Mid-Carolina High School |
| 6 | SR | Horn | A04 | Nick Bishop | Boiling Springs High School |
| 6 | SR | Trombone | 01 | Henry Niehaus | York Comprehensive High School |
| 6 | SR | Trombone | 02 | Andrew Greer | James F. Byrnes High School |
| 6 | SR | Trombone | 03 | Seth Edwards | Chapman High School |
| 6 | SR | Trombone | 04 | Jonathan Arcamone | Boiling Springs High School |
| 6 | SR | Trombone | 05 | Scottie Edwards | Blacksburg High School |
| 6 | SR | Trombone | 06 | Jadakus Coker | Boiling Springs High School |
| 6 | SR | Trombone | 07 | Timothy Moore | James F. Byrnes High School |
| 6 | SR | Trombone | 08 | Garrett Davis | James F. Byrnes High School |
| 6 | SR | Trombone | 09 | Drake Frazier | Clover High School |
| 6 | SR | Trombone | A01 | Brandon Lueth | York Comprehensive High School |
| 6 | SR | Trombone | A02 | Erin Foster | Chapman High School |
| 6 | SR | Trombone | A03 | Parker Burgess | Dorman High School |
| 6 | SR | Euphonium | 01 | Autumn Rice | York Comprehensive High School |
| 6 | SR | Euphonium | 02 | Kendal Conley | Lawson Academy of the Arts Home School Band |
| 6 | SR | Euphonium | 03 | Alex Doolittle | Boiling Springs High School |
| 6 | SR | Euphonium | 04 | Courtney Grose | York Comprehensive High School |
| 6 | SR | Euphonium | A01 | Aaron Anderson | James F. Byrnes High School |
| 6 | SR | Euphonium | A02 | Kari Young | Clinton High School |
| 6 | SR | Tuba | 01 | Adeshwa Smith | Union County High School |
| 6 | SR | Tuba | 02 | Matthew Kinnerson | Clover High School |
| 6 | SR | Tuba | 03 | Conner Saunders | James F. Byrnes High School |
| 6 | SR | Tuba | 04 | Stephen Lewis | Dorman High School |
| 6 | SR | Tuba | 05 | Montel Thompson | Dorman High School |
| 6 | SR | Tuba | 06 | Brentley Fravel | Boiling Springs High School |
| 6 | SR | Tuba | 07 | Elijah Glankler | Clover High School |
| 6 | SR | Tuba | 08 | Jaelin Gossett | York Comprehensive High School |
| 6 | SR | Tuba | A01 | Mequil Waller | Spartanburg High School |
| 6 | SR | Tuba | A02 | Nicholas Wright | Gaffney Senior High School |
| 6 | SR | Tuba | A03 | Wyatt Rolison | Blacksburg High School |
| 6 | SR | Tuba | A04 | Adam Bachmann | York Comprehensive High School |
| 6 | SR | Bass Trombone | 01 | Jon Callahan | Laurens District 55 High School |
| 6 | SR | Bass Trombone | A01 | Angel McJunkin | Boiling Springs High School |
| 6 | SR | Percussion | 01 | Jackson Wiley | James F. Byrnes High School |
| 6 | SR | Percussion | 02 | Eli Manke | Spartanburg High School |
| 6 | SR | Percussion | 03 | Anna Moore | Dorman High School |
| 6 | SR | Percussion | 04 | Colin Clinton | York Comprehensive High School |
| 6 | SR | Percussion | 05 | Eric Elswick | York Comprehensive High School |
| 6 | SR | Percussion | 06 | Evony Reddish | Chapman High School |
| 6 | SR | Percussion | 07 | Christian Broadwell | York Comprehensive High School |
| 6 | SR | Percussion | A01 | Ria Shah | Dorman High School |
| 6 | SR | Percussion | A02 | Ethan Platt | James F. Byrnes High School |
| 6 | SR | Percussion | A03 | Kimberly Fuhman | Clinton High School |
| 6 | SR | Percussion | A04 | Jonah Fleming | Clover High School |
| 6 | SR | Timpani | 01 | Jayden Milbry | Clover High School |