| Region | Level | Instrument | Chair | Name | School |
| 5 | CL | Flute | 01 | Madison Liles | Cane Bay High School |
| 5 | CL | Flute | 02 | RJ Grant | Goose Creek High School |
| 5 | CL | Flute | 03 | Kayla Moses | West Florence High School |
| 5 | CL | Flute | 04 | Taylor Pittman | Stratford High School |
| 5 | CL | Flute | 05 | Rafael Castellanos | Hanahan High School |
| 5 | CL | Flute | 06 | Sydney Ballard | Hanahan High School |
| 5 | CL | Flute | 07 | Samantha Wheelis | Cane Bay High School |
| 5 | CL | Flute | 08 | Jenny Le | Hanahan High School |
| 5 | CL | Flute | 09 | Jennifer Polfleit | Stratford High School |
| 5 | CL | Flute | 10 | Jemiah Williams | Stratford High School |
| 5 | CL | Flute | 11 | Lilly Ellis | Goose Creek High School |
| 5 | CL | Flute | 12 | Casidy Bean | Carolina Forest High School |
| 5 | CL | Flute | A01 | Miranda Byork | North Myrtle Beach High School |
| 5 | CL | Flute | A02 | Mary McBane | Hanahan High School |
| 5 | CL | Flute | A03 | Sofia Benthall | Cheraw High School |
| 5 | CL | Flute | A04 | Yaniesha Tedder | Darlington High School |
| 5 | CL | Flute | A05 | Madison Davis | Aynor High School |
| 5 | CL | Flute | A06 | Simone Gibson | Lakewood High School |
| 5 | CL | Oboe | 01 | Robert Burleson | Goose Creek High School |
| 5 | CL | Oboe | 02 | Bailey Brooks | North Myrtle Beach High School |
| 5 | CL | Oboe | 03 | Ashlynn Andrews | Hanahan High School |
| 5 | CL | Oboe | 04 | Kiyona Trevino | Goose Creek High School |
| 5 | CL | Oboe | A01 | Michela Urso | Carolina Forest High School |
| 5 | CL | Bassoon | 01 | Aaron Nealy | Carolina Forest High School |
| 5 | CL | Bassoon | 02 | Caitlyn Liles | Cane Bay High School |
| 5 | CL | Bassoon | 03 | Ethan Wood | Hanahan High School |
| 5 | CL | Bassoon | 04 | Shalyn Russell | Cane Bay High School |
| 5 | CL | Clarinet | 01 | Hanah Kerrigan | Cane Bay High School |
| 5 | CL | Clarinet | 02 | Shaniya McInnis | Dillon High School |
| 5 | CL | Clarinet | 03 | Donovan Massey | Saint James High School |
| 5 | CL | Clarinet | 04 | Savannah Holley | Goose Creek High School |
| 5 | CL | Clarinet | 05 | Emma Grimes | Carolina Forest High School |
| 5 | CL | Clarinet | 06 | Jerkaiya Carter | Goose Creek High School |
| 5 | CL | Clarinet | 07 | JaMya Jackson | Loris High School |
| 5 | CL | Clarinet | 08 | Brianna Johnson | Georgetown High School |
| 5 | CL | Clarinet | 09 | Emma Butch | Stratford High School |
| 5 | CL | Clarinet | 10 | Isabelle Cabales | Goose Creek High School |
| 5 | CL | Clarinet | 11 | Antania McCollum | Dillon High School |
| 5 | CL | Clarinet | 12 | Yesenia Martinez | North Myrtle Beach High School |
| 5 | CL | Clarinet | 13 | Savannah Pender | Waccamaw High School |
| 5 | CL | Clarinet | 14 | Raven Colbert | Hanahan High School |
| 5 | CL | Clarinet | 15 | Nia Misuraca | Hanahan High School |
| 5 | CL | Clarinet | 16 | Evan McKinnon | Philip Simmons High School |
| 5 | CL | Clarinet | 17 | Dana Joe | Darlington High School |
| 5 | CL | Clarinet | 18 | Calye Evans | Socastee High School |
| 5 | CL | Clarinet | 19 | Alaura Stanley | Socastee High School |
| 5 | CL | Clarinet | 20 | Maya Youssef | Hanahan High School |
| 5 | CL | Clarinet | 21 | Madison Lynn | Mayo High School |
| 5 | CL | Clarinet | 22 | Shymia Scipio | Mayo High School |
| 5 | CL | Clarinet | 23 | Kayla Morin | Carolina Forest High School |
| 5 | CL | Clarinet | 24 | Logan Szyjkowski | Stratford High School |
| 5 | CL | Clarinet | A01 | Sidney Clark | Hanahan High School |
| 5 | CL | Clarinet | A02 | Vicki Hamill | Cane Bay High School |
| 5 | CL | Clarinet | A03 | Qingyi Tan | Wilson High School |
| 5 | CL | Clarinet | A04 | Sophia Lefew | Hartsville High School |
| 5 | CL | Clarinet | A05 | Emily Lamere | Central High School |
| 5 | CL | Clarinet | A06 | Victor Sanchez | Conway High School |
| 5 | CL | Clarinet | A07 | Anthony Molina-Alcazar | Socastee High School |
| 5 | CL | Clarinet | A08 | Dasia Council | Carolina Forest High School |
| 5 | CL | Bass Clarinet | 01 | Christoper Melendez | Socastee High School |
| 5 | CL | Bass Clarinet | 02 | Ashleigh Hamilton | Goose Creek High School |
| 5 | CL | Bass Clarinet | 03 | Jada Davis | Dillon High School |
| 5 | CL | Bass Clarinet | 04 | Jackson Farmer | Hanahan High School |
| 5 | CL | Bass Clarinet | A01 | Maria Munoz | Darlington High School |
| 5 | CL | Bass Clarinet | A02 | Ali Small | Hartsville High School |
| 5 | CL | Contra Clarinet | 01 | Rebekah Morton | Goose Creek High School |
| 5 | CL | Alto Sax | 01 | Sarah Dumont | Stratford High School |
| 5 | CL | Alto Sax | 02 | Leslie Orellana | Sumter High School |
| 5 | CL | Alto Sax | 03 | Jamont McRae | Dillon High School |
| 5 | CL | Alto Sax | 04 | Kevin Spivey | Stratford High School |
| 5 | CL | Alto Sax | 05 | Jerrell Nesbitt | Lake City High School |
| 5 | CL | Alto Sax | 06 | McKinley Mingacci | Stratford High School |
| 5 | CL | Alto Sax | A01 | Zachary Santarelli | Hanahan High School |
| 5 | CL | Alto Sax | A02 | Abigail Alsbrooks | Sumter High School |
| 5 | CL | Alto Sax | A03 | Jason Almaraz | Goose Creek High School |
| 5 | CL | Tenor Sax | 01 | Chase Sawyer | Latta High School |
| 5 | CL | Tenor Sax | 02 | Justin Gilkerson | Stratford High School |
| 5 | CL | Tenor Sax | A01 | Landon Bailey | Sumter High School |
| 5 | CL | Bari Sax | 01 | Christopher Hancock | Darlington High School |
| 5 | CL | Bari Sax | A01 | Yu’nique Dawkins | Dillon High School |
| 5 | CL | Trumpet | 01 | Michael Walton | Carolina Forest High School |
| 5 | CL | Trumpet | 02 | Jacob Spell | Cane Bay High School |
| 5 | CL | Trumpet | 03 | Jack DeRiso | Saint James High School |
| 5 | CL | Trumpet | 04 | Jaedon Rush | Goose Creek High School |
| 5 | CL | Trumpet | 05 | Cameron McDuffie | Sumter High School |
| 5 | CL | Trumpet | 06 | Aiden Davis | Sumter High School |
| 5 | CL | Trumpet | 07 | Allison Brown | Cheraw High School |
| 5 | CL | Trumpet | 08 | Wayne Belisle | Cane Bay High School |
| 5 | CL | Trumpet | 09 | Benjamin Green | Wilson High School |
| 5 | CL | Trumpet | 10 | Logan Carpenter | Stratford High School |
| 5 | CL | Trumpet | 11 | Terry Boyd | Cross High School |
| 5 | CL | Trumpet | 12 | Storm Milon | Socastee High School |
| 5 | CL | Trumpet | 13 | Kenneth Wingate | Hartsville High School |
| 5 | CL | Trumpet | 14 | Jullia Gifford | Socastee High School |
| 5 | CL | Trumpet | 15 | Ben Battelini | Stratford High School |
| 5 | CL | Trumpet | 16 | Hakeem Cain | Wilson High School |
| 5 | CL | Trumpet | A01 | Jalik Wright | Dillon High School |
| 5 | CL | Trumpet | A02 | Shayklin Adams | Timberland High School |
| 5 | CL | Trumpet | A03 | Ashanti Milling | Darlington High School |
| 5 | CL | Trumpet | A04 | Florencio Hernandez | Goose Creek High School |
| 5 | CL | Trumpet | A05 | Ashton Turner | Dillon High School |
| 5 | CL | Trumpet | A06 | Olivia Witcher | Stratford High School |
| 5 | CL | Trumpet | A07 | Glenn Braden | Sumter High School |
| 5 | CL | Trumpet | A08 | Thomas Hirak | Sumter High School |
| 5 | CL | Horn | 01 | Isabella Hirsch | Carolina Forest High School |
| 5 | CL | Horn | 02 | Joseph Clayborne | Sumter High School |
| 5 | CL | Horn | 03 | DeAndre Lloyd | Goose Creek High School |
| 5 | CL | Horn | 04 | Haley Bullock | Goose Creek High School |
| 5 | CL | Horn | 05 | Abaigail Stewart | Socastee High School |
| 5 | CL | Horn | 06 | Jada Goff | Socastee High School |
| 5 | CL | Horn | 07 | Laney Midgley | Cheraw High School |
| 5 | CL | Horn | 08 | Marissa Moore | Cane Bay High School |
| 5 | CL | Horn | A01 | Evie O’Saben | Stratford High School |
| 5 | CL | Horn | A02 | Colby Gerald | Loris High School |
| 5 | CL | Horn | A03 | Carson Mack | Central High School |
| 5 | CL | Horn | A04 | Ashanti Tyson | Dillon High School |
| 5 | CL | Trombone | 01 | Elsie Brumett | Chesterfield High School |
| 5 | CL | Trombone | 02 | Olivia Walker | Stratford High School |
| 5 | CL | Trombone | 03 | Xavier Wright | Wilson High School |
| 5 | CL | Trombone | 04 | Everard Seay | Latta High School |
| 5 | CL | Trombone | 05 | Ethan Strickland | Wilson High School |
| 5 | CL | Trombone | 06 | Xavier McKinley | Lakewood High School |
| 5 | CL | Trombone | 07 | Lilly Summers | Goose Creek High School |
| 5 | CL | Trombone | 08 | Te’Ondrus Billie | Sumter High School |
| 5 | CL | Trombone | 09 | TJ Pitchford | Cane Bay High School |
| 5 | CL | Trombone | A01 | Preston Bishop-Burns | North Myrtle Beach High School |
| 5 | CL | Trombone | A02 | Benjamin Springle | Stratford High School |
| 5 | CL | Trombone | A03 | Richard Thompson | Socastee High School |
| 5 | CL | Trombone | A04 | James Suggs | South Florence High School |
| 5 | CL | Trombone | A05 | Matthew Villanueva | Goose Creek High School |
| 5 | CL | Bass Trombone | 01 | Michael Goosens | Stratford High School |
| 5 | CL | Euphonium | 01 | Russell Brown | Carolina Forest High School |
| 5 | CL | Euphonium | 02 | Katie Susol | Hanahan High School |
| 5 | CL | Euphonium | 03 | David Felix | Wilson High School |
| 5 | CL | Euphonium | 04 | Alyssa Ruppe | Loris High School |
| 5 | CL | Euphonium | A01 | McKenzie Oliver | Cheraw High School |
| 5 | CL | Euphonium | A02 | Paul McCullough | Socastee High School |
| 5 | CL | Tuba | 01 | Jacob Zenner | Goose Creek High School |
| 5 | CL | Tuba | 02 | Tray Kelly | Chesterfield High School |
| 5 | CL | Tuba | 03 | Bryanna Jackson | Timberland High School |
| 5 | CL | Tuba | 04 | Carson Woodham | Cheraw High School |
| 5 | CL | Tuba | 05 | Derek Taylor | Goose Creek High School |
| 5 | CL | Tuba | 06 | Darnell Davis | Dillon High School |
| 5 | CL | Tuba | 07 | Javarea Scott | Wilson High School |
| 5 | CL | Tuba | 08 | Josh Gabbey | Hartsville High School |
| 5 | CL | Tuba | A01 | Symeon Kennedy | Goose Creek High School |
| 5 | CL | Tuba | A02 | Jayvon Simmons | Goose Creek High School |
| 5 | CL | Tuba | A03 | DeQuincy Love | Hartsville High School |
| 5 | CL | Tuba | A04 | Aalayja Washington | Hanahan High School |
| 5 | CL | Percussion | 01 | Cailin Ramos | Stratford High School |
| 5 | CL | Percussion | 02 | Jackson Knight | Hanahan High School |
| 5 | CL | Percussion | 03 | Lucas Trosper | Sumter High School |
| 5 | CL | Percussion | 04 | Wyatt Carhart | Hanahan High School |
| 5 | CL | Percussion | 05 | Michael Pickler | Goose Creek High School |
| 5 | CL | Percussion | 06 | Sebastian Carrasco | Goose Creek High School |
| 5 | CL | Percussion | 07 | Jessica Rock | Cane Bay High School |
| 5 | CL | Percussion | A01 | Palmer Robbins | Sumter High School |
| 5 | CL | Percussion | A02 | Calece Kornahrens | Hanahan High School |
| 5 | CL | Percussion | A03 | Harold Chandler | Goose Creek High School |
| 5 | CL | Percussion | A04 | Dante Aguilar | Goose Creek High School |
| 5 | CL | Timpani | 01 | Betty Rugema | Goose Creek High School |
| 5 | CL | Timpani | A01 | Covington Loftus | Waccamaw High School |