| Region | Level | Instrument | Chair | Name | School |
| 4 | SR | Flute | 01 | Jessica Boyd | Charleston School of the Arts High School |
| 4 | SR | Flute | 02 | Andrew Smith-Jones | Ashley Ridge High School |
| 4 | SR | Flute | 03 | Aniya Euland | Fort Dorchester High School |
| 4 | SR | Flute | 04 | Berkeley Robinson | Wando High School |
| 4 | SR | Flute | 05 | Daniella Swehla | Summerville High School |
| 4 | SR | Flute | 06 | Sarah Whitaker | Wando High School |
| 4 | SR | Flute | 07 | Cassondra Lester | Wando High School |
| 4 | SR | Flute | 08 | Brynnan Frye | Charleston School of the Arts High School |
| 4 | SR | Flute | 09 | Cameron Hughes | Wando High School |
| 4 | SR | Flute | 10 | Olivia Arehart | Wando High School |
| 4 | SR | Flute | 11 | Mackinzie Hills | Wando High School |
| 4 | SR | Flute | 12 | Sara Dannible | Ashley Ridge High School |
| 4 | SR | Flute | A1 | Dartagnan Brownlee | Ashley Ridge High School |
| 4 | SR | Flute | A2 | Janey Whitley | Wando High School |
| 4 | SR | Flute | A3 | Hannah Ramelb | Ashley Ridge High School |
| 4 | SR | Flute | A4 | McHenry Jackson | Charleston School of the Arts High School |
| 4 | SR | Flute | A5 | Cassidy Carter | Colleton County High School |
| 4 | SR | Flute | A6 | Tina Tran | Bluffton High School |
| 4 | SR | Oboe | 01 | Madison Craig | Charleston School of the Arts High School |
| 4 | SR | Bassoon | 01 | Caitlyn Van de Meulebroecke | Wando High School |
| 4 | SR | Bassoon | 02 | Coleman Jones | Charleston School of the Arts High School |
| 4 | SR | Bassoon | 03 | Shad Burkett | Summerville High School |
| 4 | SR | Bassoon | 04 | Joseph McGuinn | Charleston School of the Arts High School |
| 4 | SR | Bassoon | A1 | Rebecca Simmons | Ashley Ridge High School |
| 4 | SR | Clarinet | 01 | Corey Palmer | Ashley Ridge High School |
| 4 | SR | Clarinet | 02 | Alexia Charles | Fort Dorchester High School |
| 4 | SR | Clarinet | 03 | Hayley Schopfer | Summerville High School |
| 4 | SR | Clarinet | 04 | Hunter Garner | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 05 | Hannah Culler | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 06 | Allison Fister | Wando High School |
| 4 | SR | Clarinet | 07 | Colleen Pia | Ashley Ridge High School |
| 4 | SR | Clarinet | 08 | Lucy Wyke-Smith | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 09 | Tiamoni Garner | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 10 | Hana Guerriere | Wando High School |
| 4 | SR | Clarinet | 11 | Abigail Long | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 12 | Breanna Bonomo | Wando High School |
| 4 | SR | Clarinet | 13 | Izzy Gustafson | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 14 | Ethan Lo | Wando High School |
| 4 | SR | Clarinet | 15 | Maria Manaeva | Colleton County High School |
| 4 | SR | Clarinet | 16 | Mark Steffan | James Island Charter High School |
| 4 | SR | Clarinet | 17 | Jasper Neath | Porter Gaud School |
| 4 | SR | Clarinet | 18 | Brooklyn Davis | Fort Dorchester High School |
| 4 | SR | Clarinet | 19 | Jordan Douglas | Charleston School of the Arts High School |
| 4 | SR | Clarinet | 20 | Lea Bell | Wando High School |
| 4 | SR | Clarinet | 21 | Brennan Holmes | Wade Hampton High School (Hampton) |
| 4 | SR | Clarinet | 22 | Dalton Tourout | Bluffton High School |
| 4 | SR | Clarinet | 23 | Jordan Alston | Wando High School |
| 4 | SR | Clarinet | 24 | Jarret Brogdon | Charleston School of the Arts High School |
| 4 | SR | Clarinet | A1 | Amari Marsh | Orangeburg Wilkinson Senior High School |
| 4 | SR | Clarinet | A2 | Alex Lopez Vara | Porter Gaud School |
| 4 | SR | Clarinet | A3 | Katie Brown | Charleston School of the Arts High School |
| 4 | SR | Clarinet | A4 | Gracie Leftwich | Summerville High School |
| 4 | SR | Clarinet | A5 | Gavin Zimmerman | May River High School |
| 4 | SR | Clarinet | A6 | Gabriel Nkhata | Orangeburg Wilkinson Senior High School |
| 4 | SR | Clarinet | A7 | Irvin Espinoza | Ridgeland Hardeeville High School |
| 4 | SR | Clarinet | A8 | Shakayla Gill | Colleton County High School |
| 4 | SR | Bass Clarinet | 01 | Jacob McGrady | Summerville High School |
| 4 | SR | Bass Clarinet | 02 | Heath DuBose | Charleston School of the Arts High School |
| 4 | SR | Bass Clarinet | 03 | Matilda Seay | Wando High School |
| 4 | SR | Bass Clarinet | 04 | Ginny Merrill | Charleston School of the Arts High School |
| 4 | SR | Bass Clarinet | A1 | Keon Johnson | Lake Marion High School |
| 4 | SR | Bass Clarinet | A2 | Mary Beth Noble | Wando High School |
| 4 | SR | Contra Clarinet | 01 | Keonna Johnson | Lake Marion High School |
| 4 | SR | Contra Clarinet | 02 | Dylan Ashlock | Summerville High School |
| 4 | SR | Alto Sax | 01 | Jack Johnson | Wando High School |
| 4 | SR | Alto Sax | 02 | Tyree Nesbitt | Summerville High School |
| 4 | SR | Alto Sax | 03 | AJ Johnston | Wando High School |
| 4 | SR | Alto Sax | 04 | Zachary Worrall | Wando High School |
| 4 | SR | Alto Sax | 05 | Nicholas Yinger | Summerville High School |
| 4 | SR | Alto Sax | 06 | Austin Ehrhardt | Edisto High School |
| 4 | SR | Alto Sax | A1 | Kate Dantzscher | Wando High School |
| 4 | SR | Alto Sax | A2 | Megan Ralfe | Wando High School |
| 4 | SR | Alto Sax | A3 | Connor Scarberry | Summerville High School |
| 4 | SR | Tenor Sax | 01 | Charlie Worrall | Wando High School |
| 4 | SR | Tenor Sax | 02 | Ashton Courtney | Wando High School |
| 4 | SR | Tenor Sax | A1 | Steven Tanner | Charleston School of the Arts High School |
| 4 | SR | Bari Sax | 01 | Finn Mefford | Wando High School |
| 4 | SR | Bari Sax | A1 | Alex Chavez | Wando High School |
| 4 | SR | Trumpet | 01 | Sabrina Linke | Ashley Ridge High School |
| 4 | SR | Trumpet | 02 | Nathan Dolbir | Wando High School |
| 4 | SR | Trumpet | 03 | Paul Meza | Fort Dorchester High School |
| 4 | SR | Trumpet | 04 | Melanie Clark | Wando High School |
| 4 | SR | Trumpet | 05 | Jacob Zetrouer | Wando High School |
| 4 | SR | Trumpet | 06 | Braeden Armbruster | Wando High School |
| 4 | SR | Trumpet | 07 | West Law | Wando High School |
| 4 | SR | Trumpet | 08 | Joey Salata | Wando High School |
| 4 | SR | Trumpet | 09 | George Higgins | Summerville High School |
| 4 | SR | Trumpet | 10 | Matthew Pitassi | Wando High School |
| 4 | SR | Trumpet | 11 | Alex Camp | Wando High School |
| 4 | SR | Trumpet | 12 | Gabe Cutter | Wando High School |
| 4 | SR | Trumpet | 13 | Victor Tuk | Wando High School |
| 4 | SR | Trumpet | 14 | Daniel Putman | Wando High School |
| 4 | SR | Trumpet | 15 | Evan Geiger | Wando High School |
| 4 | SR | Trumpet | 16 | Jonathan Bezy | Bluffton High School |
| 4 | SR | Trumpet | A1 | Jordan Pate | Wando High School |
| 4 | SR | Trumpet | A2 | Cady Haller | Charleston School of the Arts High School |
| 4 | SR | Trumpet | A3 | Amanda Lapin | Wando High School |
| 4 | SR | Trumpet | A4 | William Forsyth | West Ashley High School |
| 4 | SR | Trumpet | A5 | Jacob Gamble | Ashley Ridge High School |
| 4 | SR | Trumpet | A6 | Daniel Brown | Charleston School of the Arts High School |
| 4 | SR | Trumpet | A7 | Matthew Wagner | May River High School |
| 4 | SR | Trumpet | A8 | Christian Wilson | Fort Dorchester High School |
| 4 | SR | Horn | 01 | Cecile Thomson | Charleston School of the Arts High School |
| 4 | SR | Horn | 02 | Maggie Tennant | Charleston School of the Arts High School |
| 4 | SR | Horn | 03 | Maggie Scapellato | Charleston School of the Arts High School |
| 4 | SR | Horn | 04 | Samuel Solomons | Barnwell High School |
| 4 | SR | Horn | 05 | Chloe Bright | Ashley Ridge High School |
| 4 | SR | Horn | 06 | Sadie Bates | Ashley Ridge High School |
| 4 | SR | Horn | 07 | Holly Hauschild | Fort Dorchester High School |
| 4 | SR | Horn | 08 | Stuart Saletan | Wando High School |
| 4 | SR | Horn | A1 | Caitlin Brennan | Charleston School of the Arts High School |
| 4 | SR | Horn | A2 | Lillie Thomas | Wando High School |
| 4 | SR | Horn | A3 | Cecilia Wright | Beaufort High School |
| 4 | SR | Horn | A4 | Mikayla Wyandt | James Island Charter High School |
| 4 | SR | Trombone | 01 | Savannah Mellichamp | Wando High School |
| 4 | SR | Trombone | 02 | Jaclyn Normoyle | Fort Dorchester High School |
| 4 | SR | Trombone | 03 | Tradd Saxton | Wando High School |
| 4 | SR | Trombone | 04 | William Knudson | Wando High School |
| 4 | SR | Trombone | 05 | Keven Sheperd | Burke High School |
| 4 | SR | Trombone | 06 | Ana White | Wando High School |
| 4 | SR | Trombone | 07 | Hunter DuBose | Charleston School of the Arts High School |
| 4 | SR | Trombone | 08 | Anthony Crimely | Colleton County High School |
| 4 | SR | Trombone | 09 | Walker King | Charleston School of the Arts High School |
| 4 | SR | Trombone | A1 | Haley Swittenberg | Charleston School of the Arts High School |
| 4 | SR | Euphonium | 01 | Camila Dorst | Wando High School |
| 4 | SR | Euphonium | 02 | Matteo Medina | Wando High School |
| 4 | SR | Euphonium | 03 | Aleric Stell | Fort Dorchester High School |
| 4 | SR | Euphonium | 04 | Jatavian Reese | Wade Hampton High School (Hampton) |
| 4 | SR | Euphonium | A1 | Robert Dent | Colleton County High School |
| 4 | SR | Euphonium | A2 | Gilberto Costilla | Bluffton High School |
| 4 | SR | Tuba | 01 | Tucker Nelson | Wando High School |
| 4 | SR | Tuba | 02 | Alex Bailey | Wando High School |
| 4 | SR | Tuba | 03 | Grace Wagner | Ashley Ridge High School |
| 4 | SR | Tuba | 04 | Micah Pearson | Charleston School of the Arts High School |
| 4 | SR | Tuba | 05 | Christopher Jones | Orangeburg Wilkinson Senior High School |
| 4 | SR | Tuba | 06 | Michael Jaldin-Soto | West Ashley High School |
| 4 | SR | Tuba | 07 | Martin Barye-Garcia | Charleston School of the Arts High School |
| 4 | SR | Tuba | 08 | John Jones | James Island Charter High School |
| 4 | SR | Tuba | A1 | Drew Marx | Wando High School |
| 4 | SR | Tuba | A2 | Crystal Waymyers | North High School |
| 4 | SR | Tuba | A3 | Patrick Myers | Charleston School of the Arts High School |
| 4 | SR | Tuba | A4 | Brandon Dukes | Summerville High School |
| 4 | SR | Percussion | 01 | Tyler Epperson | Wando High School |
| 4 | SR | Percussion | 02 | Trevor Byrum | Ashley Ridge High School |
| 4 | SR | Percussion | 03 | John Robinson | Wando High School |
| 4 | SR | Percussion | 04 | Colin Sandman | Bluffton High School |
| 4 | SR | Percussion | 05 | Will Flinner | Ashley Ridge High School |
| 4 | SR | Percussion | 06 | Alex Tuck | Wando High School |
| 4 | SR | Percussion | 07 | Jim Wilborn | Wando High School |
| 4 | SR | Percussion | A1 | Rachel Huggins | Summerville High School |
| 4 | SR | Percussion | A2 | Anna Li Lewis | Wando High School |
| 4 | SR | Percussion | A3 | Mason Malone | Wando High School |
| 4 | SR | Percussion | A4 | Patrick Brooks | Summerville High School |
| 4 | SR | Timpani | 01 | Eric Holmi | Wando High School |
| 4 | SR | Timpani | A1 | Haley Edwards | Allegro Music Charter School |