From I-26 W (Spartanburg): Go I-26 East to Columbia.  Get on I-20 West toward Augusta.  Take exit 61 (US Hwy 378) to Lexington.  Stay on US 378 until it merges with US 1 in Lexington.  Then stay on US 1.  After you pass Ben Satcher Ford go through three traffic lights, and Lexington High School is on the left. 

From I-26 E (Charleston): Go I-26 West to Columbia.  Take exit 110 (US Hwy 378) to Lexington.  Stay on US 378 until it merges with US 1 in Lexington.  Then stay on US 1.  After you pass Ben Satcher Ford go through three traffic lights, and Lexington High School is on the left. 

From I-20 E (Florence): Go I-20 West through Columbia. Take exit 61 (US Hwy 378) to Lexington.  Stay on US 378 until it merges with US 1 in Lexington.  Then stay on US 1.  After you pass Ben Satcher Ford go through three traffic lights, and Lexington High School is on the left.

From I-20 W (North Augusta): Go I-20 East to exit 51 (SC 204).  Turn left to cross back over I-20.  Go to the second traffic light, and turn left onto US 1 (approx. 4 miles from I-20).  Lexington High School is on the left.